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29 Cards in this Set
- Front
- Back
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When does the CL regress in non-pregnant?
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14 days
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When does placental P4 take over in pregnancy?
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7-9 weeks
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What test do you order for confirmation of pregnancy?
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BhCG
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Plasma volume, red cell mass, renal blood flow, heart rate, tidal volume, and weght do what in pregnancy?
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Increase
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Gastric motility, esophgeal spichter tone, osmolality do what in pregnancy?
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Decrease
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What increases at the pituitary gland with pregnancy?
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Size
Prolactin Oxytocin ACTH |
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What decreases at the pituitary gland with pregnancy?
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FSH
LH |
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What changes occur at the thyroid gland during pregnancy?
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Increase size
Increase in total T4 and T3 |
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What happens to the parathyroid gland in pregnancy?
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Increase in size
Increase in PTH |
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What happens with the pancrease during pregnancy?
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hyperplasia and hypertrophy of B cells
Increase insulin secretion |
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What happens to the adrenal cortex during pregnancy?
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Increase in:
Response to ACTH Cortisol secretion Liver production of cortisol binding globulin Aldosterone |
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Which hormones are usually causing changes in glands when prego?
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E2
hPL/PRL hCG P4 |
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What are three peptide hormones produced by the placenta?
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hCG
hPL (placental lactogen) CRH (cortisol releasing hormone) |
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What are two steroid hormones produced by the placenta?
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Progesterone
Estrogens (estriol) |
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What is a disease in which women who aren't pregnant have hCG present?
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gestational trophoblastic disease
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hPL is related to which hormones?
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GH and prolactin (PRL)
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What are some action of hPL?
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+ IGF-1
+ pancreatinc insulin secretion + pancreatic B cell proliferation + lipolysis |
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What does CRH from placenta do?
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+ by glucocorticoids (unlike hypothalamic CRH)
+ PG production + fetal ACTH secretion |
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Does the placenta produce androgens?
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NO
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Does the fetus produce P4?
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NO, placenta makes it
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Does the fetus make estrogen?
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NO but makes DHEAS
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What is the role of progesterone in the myometrium?
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Prevent contractions by inhibiting COX-2, CAP, OT
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What does P4 do to mom's immune system?
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Supress it
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What does estrogen do to PG production?
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Increase it
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What does estrogen do to the myometrium?
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Increase gap jct, CAP, OT receptors
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What is the change in P4 to E2 in parturition?
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P4 goes down
E2 goes UP |
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What are the key hormones in parturition?
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CHR
PGs OT |
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What is the ferguson reflex?
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OT increases which increases contractions which increases OT
Feed forward |
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What does prostaglandins do in the myometrium?
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Increase gap jcts
Increase contractions Softens the cervix |
