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25 Cards in this Set
- Front
- Back
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How would you prepare a Aldehyde? (aldehyde synthesis is by oxidation of primary alcohols) |
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How would you prepare an Aldehyde from Alkene--> Olefin (double bond at alpha carbon) |
1.O3 2.Zn, H+ ---> |
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How would you prepare an Aldehyde from an Ester? |
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How would you prepare a Ketone from an Alkene(Olefin) |
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How would you prepapre a Ketone from a Secondary ROH |
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Prepare an Ketone from an aromatic ring? -add ketone to an aromatic ring |
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Prepare a Ketone from an acid chloride? |
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Prepare a ketone from a Alkyne? |
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Aldeyhde to Carboxylic acid |
-use H3O instead of H2O? |
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What are more reactive? Aldeyhdes or ketones? and due to what 2 things? |
Aldehydes 1) due to sterics 2) due to electronics |
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base-catalyzed "Hydration" of Aldeyhdes and Ketones |
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acid-catalyzed "Hydration" of Aldehydes and Ketones |
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-CN addition of Aldehydes/Ketones "Cyanohydrin formation" |
ONLY BASE-CATALYZED |
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Nu: addition to Aldeyhdes and Ketones (make a new C-C bond) |
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Primary Amine addition (RNH2) to aldeyhes/ketones IMINE MECHANISM |
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ENAMINE MECHANISM |
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ALdeyhyde/ketone "Wolff-Kishner Reaction" special amine reaction with hydrazine, followed by a strong base -reduce to alkanes |
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ROH addition, acid-catalyzed Ketone --> ketal Aldehyde --> Acetal |
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Ketone/Aldeyhe to alkene |
phosohorus Ylide Nu: |
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1,2 addition to C=O |
Grignard and R-Li |
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1,4 addition to C=O "Micheal addition", "Conjugate Addition" alpha,beta -unsaturated carbonyls (aldehydes and ketones) |
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1,4 amine addition |
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1,4 Cuprate R:- addition |
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2-cyclohexenone 1) Gridnard and R-Li / H3O+ give... 2) Cuprates give... |
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Ketone and Aldeyhde. Protect group for C=O
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