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27 Cards in this Set

  • Front
  • Back
3 processes of urine formation?
golmerular filtration
tubular absorption
tubular secretion
What does filtrate contain?
all plasma except proteins and cells
What does urine contain?
undesirable portion of the plasma
Purpose of regulating the golmerular filtration rate?
protective to the kidney, need to keep rate relatively constant
Tubuloglomerular feedback?
macula densa releases chemicals that regulate arteriole diamter
What does macula densa do when there is a high amount of filtrate flow?
release ATP that causes constriction of afferent arteriole
What does macula densa do when there is a slow amount of filtrate flow?
release nitric oxide to cause dilation of afferent arteriole
Purpose of tubular reabsorption?
prevents loss of blood components
What does active reabsorption involve? 2
secondary active transport with Na+
Tm-transport maximum
What does passive reabsorption involve? 3
-movement of ions along electrochemical gradient established by Na+
-obligatory water movement
-solvent drag
What are the non-reabsorbed substances? 3
urea
creatinine
uric acid
Where is the most metabolites reabsorbed?
proximal convoluted tubule
What is mainly involved in tubular secretion?
proximal convoluted tubule
What does tubular secrete? 3
K+, NH4+, other acids
What regulated urine volume?
countercurrent mechanism
What tubes form the countercurrent mechanism? 2
loop of henle
vasa recta
What does the descending limb of loop lose?
water
What does the ascending limb of loop lose?
Na
What does the collecting duct lose?
urea
Role of vasa recta?
absorb material from loop, collecting duct
Role of ADH in collecting duct?
increase water permeability
Amount of ADH in dilute urine?
little or no ADH
Amount of ADH in concentrated urine?
with ADH
Renal clearance?
volume of plasma from which substance is cleared per minute
What causes yellow urine?
hemoglobin breakdown
What causes urine odor?
urea and bacteria
pH of urine?
6