Kk&s Ch.18 Chronic Fatigue Syndrome

Front 1

CDC dx of chronic fatigue?

Back 1

1. Severe unexplained fatigue for over 6 months that is:
1. of a new or definite onset
2. not due to continuing exertion
3. not resolved by rest
4. functionally impairing
2. The presence of four or more of the following new symptoms:
1. impaired memory or concentration
2. sore throat
3. tender lymph nodes
4. muscle pain
5. pain in several joints
6. new pattern of headaches
7. unrefreshing sleep
8. postexertional malaise lasting more than 24 hours

Front 2

Chronic fatigue versus depression?

Back 2

CFS patients have depressive symptoms, but not guilt, suicidal ideation, or observable psychomotor slowing.

Front 3

Chronic fatigue and possible GMC?

Back 3

In some cases, a noticeable correlation exists between CFS and neuarlly mediated hypotension, an autonomic nervous system dysfunction. It has been suggested that patients presenting with CFS symptoms undergo a tilt-table test to delineate In some cases, a noticeable correlation exists between CFS and neuarlly mediated hypotension, an autonomic nervous system dysfunction. It has been suggested that patients presenting with CFS symptoms undergo a tilt-table test to delineate

Front 4

DDX of chronic fatigue?

Back 4

Chronic fatigue must be differentiated from endocrine disorders (e.g., hypothyroidism), neurological disorders (e.g., multiple sclerosis [MS]), infectious disorders (e.g., acquired immune deficiency syndrome [AIDS], infectious mononucleosis), and psychiatric disorders (e.g., depressive disorders)

Front 5

Up to ? percent of patients with chronic fatigue syndrome meet the diagnostic criteria for major depression

Back 5

80%

Front 6

Why CFS not linked totally to depression?

Back 6

Also, usually no family history of depression or other genetic loading for psychiatric disorder is found and few, if any, stressful events have occurred in patients' lives that might precipitate or account for a depressive illness.

In addition, although some patients respond to antidepressant medication, many eventually become refractory to all psychopharmacological agents.

Front 7

what is neurasthenia?

Back 7

nervous exhaustion
chronic fatigue equivalent which is placed in undifferentiated somataform ds
Neurasthenia is an accepted condition in Europe and Asia, where it is characterized by fatigue, headache, insomnia, and other vague somatic complaints and is thought to result from chronic stress rather than from unconscious psychological conflicts.