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106 Cards in this Set

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What is the most common odontogenic cyst of the jaw?
Periapical cysts aka Radicular cyst
- associated with a nonvital tooth or trauma, not always symptomatic
- necrotic dental pulp creates inflammatory response at apex leading to granuloma formation, a fistula to the gingival or even through cheek/jaw skin can occur
What are the radiographical features of a periapical/radicular cyst?
Radiolucent
Single lesion
Well-demarcated unilocular
Surrounding apex of tooth
Radiolucent
Single lesion
Well-demarcated unilocular
Surrounding apex of tooth
What is the tx of periapical/radicular cysts?
Removal of underlying inflammatory process through endodontic tx (root canal) or tooth extraction with enucleation and curettage;

Abx and drainage of any soft tissue abscess
What is a residual periapical cyst?
Cyst at the site of previous tooth extraction

Remnant of process that led to tooth loss versus insufficient curettage during tooth extraction versus continuation of epithelial rest inflammatory response after tooth extraction

Generally assx
Cyst at the site of previous tooth extraction

Remnant of process that led to tooth loss versus insufficient curettage during tooth extraction versus continuation of epithelial rest inflammatory response after tooth extraction

Generally assx
What is the second most common odontogenic cyst of the jaws?
Dentigerous cyst
Describe the clinic features of a dentigerous cyst
Associated with the crown of UNERUPTED tooth

Most commonly arises from mandibular 3rd molar or maxillary canines, altough can occur at any unerupted tooth

Can grown very large, associated with painless expansion of bone

18G needle aspirat...
Associated with the crown of UNERUPTED tooth

Most commonly arises from mandibular 3rd molar or maxillary canines, altough can occur at any unerupted tooth

Can grown very large, associated with painless expansion of bone

18G needle aspiration can yield STRAW-COLORED FLUID
What are the radiographical features of a dentigerous cyst?
Radiolucent
Single lesion
Well-demarcated unilocular
Associated with crown of UNERUPTED tooth
Tx of dentigerous cyst?
Extraction of affected tooth with enucleation and curettage

If larger cyst, may consider two-stage approach with prolonged decompression with drain prior to formal treatment
Describe the clinical features of an eryption cyst
Occurs during tooth eruptions process in children less than 10yo

BLUISH CYST appears under the gingiva, can sometimes be painful
Occurs during tooth eruptions process in children less than 10yo

BLUISH CYST appears under the gingiva, can sometimes be painful
What is the tx of an eruption cyst?
Usually not needed, resolves when tooth erupts through it; if fails to occur, then simple excision
Usually not needed, resolves when tooth erupts through it; if fails to occur, then simple excision
What are the clinical features of a lateral periodontal cyst?
Assx, only found on radiographs
Occurs in age of 40-70yo, rare in less than 30yo
About 80% occur in mandibular premolar/canine/lateral incisor area
What are the radiographical features of a lateral periodontal cyst?
Radiolucent
SIngle lesion
Well-demarcated unilocular
LATERAL to roots of vital teeth
Usually less than 1cm in size
Radiolucent
SIngle lesion
Well-demarcated unilocular
LATERAL to roots of vital teeth
Usually less than 1cm in size
What is the tx of a lateral periodontal cyst?
Enucleation with preservation of tooth
What are the clinical features of a glandular odontogenic cyst?
Middle age adults
About 80% occur in mandible, generally anterior
Small cysts can be assx, but larger ones can expand to produce pain/paresthesias
What are the readiographical features of a glandular odontogenic cyst?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular

(Histopathalogically there are mucous cells present)
What are the clinical features of Gorlin's cyst?
Gorlin's cyst = calcifying odontogenic cyst

Variable clinical behavior
Variable age, infant to elderly
Variable location, intraosseous vs extraosseous
What are the radiographical features of Gorlin's cyst?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Irregular calcifications can be present
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Irregular calcifications can be present
What is the tx of a Gorlin's cyst?
Enucleation and curettage for intraosseous
Excision for extraosseus
What is the most common NONodontogenic cyst of the jaw?
Nasopalatine duct cyst/incisive canal cyst
- forms during fusion of primary and secondary palate
- male predominance
Nasopalatine duct cyst/incisive canal cyst
- forms during fusion of primary and secondary palate
- male predominance
What are the radiographical features of nasopalatine duct cyst?
HEART SHAPED radiolucent lesion
Single lesion
Well-demarcated unilocular
Above roots of central incisors
What are the tx of nasopalatine duct cyst?
Enucleation
What are the clinical features of nasolabial cysts?
Soft tissue cyst, occurs between ala and lip from trapped epithelium during embryologic fusion; remnants of nasolacrimal duct
Female predominance, 30-50yo
Generally assx
Soft tissue cyst, occurs between ala and lip from trapped epithelium during embryologic fusion; remnants of nasolacrimal duct
Female predominance, 30-50yo
Generally assx
What are the radiographical features of nasolabial cysts?
Due to origin in soft tissues, NO radiographic changes usually present, however can sometimes saucerize adjacent bone of maxilla
What is the tx of nasolabial cysts?
Surgical excision
Name 3 pseudocysts of the jaw
Traumatic bone cyst
Aneurysmal bone cyst
Stafne bone cyst

ALL have a cystic appearance, but DO NOT have a true epithelial lining
What are the clinical features of a traumatic bone cyst?
Doe NOT necessarily have traumatic hx
Most common between ages 10-20yo
Male predominance
Affects mandible more than maxilla
18G needle aspiration yields nothing or scant blood
What are the radiographical features of a traumatic bone cyst?
Radiolucent
Single lesion
Well-demarcate multilocular
Can scallop roots of adjacent teeth
Radiolucent
Single lesion
Well-demarcate multilocular
Can scallop roots of adjacent teeth
What is the tx of a traumatic bone cyst?
Surgical exploration of cyst alone will often induce healing process
What are the clinical features of an aneurysmal bone cyst?
Affects mandible > maxilla
Rapid swelling of jaw can occur
18G needle aspiration can yield blood
What are the radiographical features of an aneurysmal bone cyst?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Can have "soap bubble" appearance
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Can have "soap bubble" appearance
What is the tx of an aneurysmal bone cyst?
Generally curettage, possible cryosurgery; resection in severe cases
What are the clinical features of a Stafne bone cyst?
Assx, radiographic finding
Thought to be developmental, may occur due to submandibular gland developing close to lingual surface leading to thinner bone formation
Inferior to mandibular canal where inferior alveolar nerve runs in posterior mandible
Most commonly unilateral
Strong male predominance
What are the radiographical features of a Stafne bone cyst?
Radiolucent
Single lesion
Well-demarcated unilocular
Radiolucent
Single lesion
Well-demarcated unilocular
What is the tx of a Stafne bone cyst?
None required
What is the most common odontogenic tumor?
Ameloblastoma - a benign, locally aggressive neoplasm
What are the clinical features of solid or multicystic (intraosseous) ameloblastoma?
Generally occurs after 20yo
About 85% occur in the mandible, most commonly in molar/ramus regions
Slow-painless expansion of jaw
What are the radiographic features of solid or multicystic (intraosseous) ameloblastoma?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Resorption of tooth roots
Cortical bone expansion
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Resorption of tooth roots
Cortical bone expansion
What are the tx options for solid or multicystic (intraosseous) ameloblastoma?
Optimal method has been controversial
Most favor resection with 1cm past radiographic extent of tumor
What are the clinical features of unicystic (intraosseous) ameloblastoma?
Majority occur int he mandibule, generally molar/ramus region
Painless swelling of the jaws
What are the radiographic features of uncystic (intraosseous) ameloblastoma?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
What are the clinical features of peripheral (extraosseous) ameloblastoma?
Middle age adult
Sessile pr pedunculated gingival mass, not ulcerated, usually posterior location
What are the radiographical features of peripheral (extraosseous) ameloblastoma?
Limited utility since extraosseous
How are malignant ameloblastoma and ameloblastic carcinoma differentiated?
Mainly based on histopathological features
- malignant ameloblastoma - no cytologic changes from benign ameloblastoma other than the fact that it is metastatic

- ameloblastic carcinoma - has malignant cytologic changes in both the primary and mets sites
How are radiogaphical features of malignant ameloblastoma and ameloblastic carcinoma?
Malignant ameloblastoma - radiolucent, single lesion, well-demarcated unilocular or multilocular

Ameloblastic carcinoma: radiolucent, single lesion, poorly defined margins (image)
Malignant ameloblastoma - radiolucent, single lesion, well-demarcated unilocular or multilocular

Ameloblastic carcinoma: radiolucent, single lesion, poorly defined margins (image)
What are clinical features of keratocystic odontogenic tumors?
Formerly known as odontogenic keratocyst (reclassified by WHO in 2005 based on genetic and histologic findings)

Majority involve the posterior body and ramuso of mandible
18G needle aspiration can yield a white/yellow, cheese-like materal
How are radiogaphical features of keratocystic odontogenic tumors?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
If there are MULTIPLE keratocystic odontogenic tumors, what syndrome does the pt need to be worked up for?
Gorlin's syndrome = Nevoid basal cell carcinoma syndrome (NBCCS)
- autosomal dominant
- multiple basal cell carcinomas
- multiple keratocystic odontogenic tumors 
- skin cysts, palmar/plantar pits
- calcified falx cerebri, increased head circ...
Gorlin's syndrome = Nevoid basal cell carcinoma syndrome (NBCCS)
- autosomal dominant
- multiple basal cell carcinomas
- multiple keratocystic odontogenic tumors
- skin cysts, palmar/plantar pits
- calcified falx cerebri, increased head circumference
- rib/vertebral malformations
- hypertelorism
- spino bifida
What are clinical features of adenomatoid odontogenic tumors?
Most coommonly below 20yo
Female predominance
Majority occur in the anterior maxilla
Slow growing, relatively assx
What are radiographical features of adenomatoid odontogenic tumors?
Radiolucent
Single lesion
Well-demarcated unilocular
May contain small calcifications which helps differentiate from dentigerous cysts
What are clinical features of calcifying epithelial odontogenic tumors?
Calcifying epithelial odontogenic tumors aka Pindborg Tumors
Generally occur between 30-50yo
More common in mandible than maxilla
Painless, slowly progressive swelling
What are radiographic features of calcifying epithelial odontogenic tumors?
Radiolucent
Single lesion
Well-demarcated multilobular
Radiolucent
Single lesion
Well-demarcated multilobular
What are the clinical and radiographical features of squamous odontogenic tumors?
Variable age and location

Radiolucent
Single
Poorly defined margins
Variable age and location

Radiolucent
Single
Poorly defined margins
What are the clinical features of ameloblastic fibroma?
Generally occur less than 30yo
Male predominance
Most common in posterior mandible
What are the radiographical features of ameloblastic fibroma?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular
What are the tx options for ameloblastic fibroma?
Initial: enucleation and curettage

Recurrence: en block resection
What are the clinical features of ameloblastic fibro-odontoma?
Most common in children
Posterior mandible
What are the radiographical features of ameloblastic fibro-odontoma?
Radiolucent
Single lesion
Well-demarcated unilocular with flecks of calcification
Radiolucent
Single lesion
Well-demarcated unilocular with flecks of calcification
What are the clinical features of ameloblastic fibrosarcoma?
ameloblastic fibrosarcoma = malignant

generally occur in young adults
Majority occur in the mandible
Pain, swelling, rapid growth

Poor prognosis
What are the radiological features of ameloblastic fibrosarcoma?
Radiolucent
SIngle lesion
Poorly defined margins
What is the tx for ameloblastic fibrosarcoma?
Radical resection
What are clinical features of odontoma?
Commonly occurs during 10-30yo
Assx, found on routine dental radiographical screening
What are radiographical features of odontoma?
ReadiOPAQUE
Single lesion
Well-demarcated
Two types:
1) compound - appears as small tooth-like structure (image)
2) complex - enamel and dentin, no resemblance of tooth
ReadiOPAQUE
Single lesion
Well-demarcated
Two types:
1) compound - appears as small tooth-like structure (image)
2) complex - enamel and dentin, no resemblance of tooth
What is the tx of odontoma?
Enucleation
What are the clinical features of central, intraosseous odontogenic fibroma?
More common after age of 40yo
Most commonly located in posterior mandible, anterior maxilla
Generally assx, may cause bony expansion or loose teeth
What are the radiographical features of central, intraosseous odontogenic fibroma?
Radiolucent
Single lesion
Well-demarcated unilocular (when small) or multilocular (when large)
Radiolucent
Single lesion
Well-demarcated unilocular (when small) or multilocular (when large)
What is the tx of central, intraosseous odontogenic fibroma?
Enucleation and curettage
What are the clinical features of peripheral, extraosseous odontogenic fibroma?
More commonly occurs in mandible
Painless expansion of bone (when large)
What are the radiographical features of peripheral, extraosseous odontogenic fibroma?
Radiolucent
Single
Well-demarcated
Unilocular or multilocular
"Soap-bubble" pattern
Appears similar to ameloblastoma
Radiolucent
Single
Well-demarcated
Unilocular or multilocular
"Soap-bubble" pattern
Appears similar to ameloblastoma
What is the tx of peripheral, extraosseous odontogenic fibroma?
resection as often locally aggressive
What are the clinical features of cementoblastoma?
Majority occur in molar/premolar region of mandible
Most common under 30yo
What are the radiographical features of cementoblastoma?
Radiopaque
Single lesion
Well-demarcated
Associated with root
Radiopaque
Single lesion
Well-demarcated
Associated with root
What is the tx of cementoblastoma?
Extraction of tooth with attached mass
Nondontogenic Tumors

What are the clinical features of osteoma's?
Young adults
Assx, slowly growing
Usually found at angle of mandible
Gardner syndrome = Autosomal dominant, colonic polyposis, multiple osteomas of the jaw, skin fibromas and impacted teeth; Need close surveillance with colonoscopy as there is a high rate of malignant transformation of colonic polyps
Nondontogenic Tumors

What are the radiographical features of osteoma's?
Radiopaque
Single lesion (can have multiple lesions of Gardner syndrome)
Well-demarcated
Radiopaque
Single lesion (can have multiple lesions of Gardner syndrome)
Well-demarcated
Nondontogenic Tumors

What is the tx of osteoma's?
Observation or surgical excision
Nondontogenic Tumors

What are the clinical features of osteoblastoma?
Commonly PAINFUL
Majority occur under age of 30yo
Nondontogenic Tumors

What are the radiographical features of osteoblastoma?
Radiopaque
Single lesion
Well-demarcated or poorly defined
Nondontogenic Tumors

What are the clinical features of osteosarcoma's?
Most common between ages 10-20yo
Equal incidence in both mandible and maxilla
Swelling, pain, loosening of teeth
Nondontogenic Tumors

What are the radiographical features of osteosarcoma's?
Radiolucent
Single lesion
Poorly defined margins or radiopaque
"SUNBURST" appearance
Widening of periodontal ligament around teeth
Radiolucent
Single lesion
Poorly defined margins or radiopaque
"SUNBURST" appearance
Widening of periodontal ligament around teeth
Nondontogenic Tumors

What are the clinical features of chondroma's?
Most common between ages 30-50yo
Most commonly located in anterior maxilla or condyle
Painless, slow growing
Nondontogenic Tumors

What are the radiographical features of chondroma's?
Radiolucent
Single lesion
Well-demarcated unilocular with central area of radiopacity
Nondontogenic Tumors

What are the clinical features of chondrosarcoma's?
Occurs in older adults
More common in maxilla than mandible
Painless swelling
Nondontogenic Tumors

What are the radiographical features of chondrosarcoma's?
Radiopaque
Single lesion
Poorly defined
Radiopaque
Single lesion
Poorly defined
Nondontogenic Tumors

What are the clinical features of fibrous dysplasia?
Generally assx
May cease or "burn out" after puberty
Two subtypes
- Monostotic, 80%
- Polyostotic (McCube-Albright syndrome: polyostotic fibrous dysplasia, cafe au lait skin lesions, endocrinopathies such as precocious puberty, pituitary or thyroid abnormalities)
Nondontogenic Tumors

What are the radiographical features of fibrous dysplasia?
Radiopaque
Single lesion
Poorly defined
"Ground glass" appearance
Radiopaque
Single lesion
Poorly defined
"Ground glass" appearance
Nondontogenic Tumors

What is the tx of fibrous dysplasia?
Observation or surgical excision
Dependent on size, location and sx severity
Nondontogenic Tumors

What are the clinical features of ossifying fibroma?
Most common between ages 20-40yo
Female predominance
More common in premolar/molar region of mandible
Painless swelling
Nondontogenic Tumors

What are the radiographical features of ossifying fibroma?
Radiolucent or radiopaque (can be mixed)
Well-demarcated unilocular
Radiolucent or radiopaque (can be mixed)
Well-demarcated unilocular
Nondontogenic Tumors

What are the clinical features of cemento-osseous dysplasia?
Strong female predominance
More common in African Americans
Middle age
Three subtypes:
1) Focal: posterior mandible
2) Periapical: anterior mandible, around tooth root
3) Florid: diffuse involvement
Nondontogenic Tumors

What are the radiographical features of cemento-osseous dysplasia?
Radiopaque
Single Lesion
Well demarcated or poorly defined
Extent depends on subtype as florid can have multiple lesions
Radiopaque
Single Lesion
Well demarcated or poorly defined
Extent depends on subtype as florid can have multiple lesions
Nondontogenic Tumors

What is the tx of cemento-osseous dysplasia?
Generally, none needed
Nondontogenic Tumors

What are the clinical features of central giant cell granuloma?
Majority occur less than 30yo
Majority occur in the mandible
Can cross midline in anterior maxilla
Nondontogenic Tumors

What are the radiographical of central giant cell granuloma?
Radiolucent
Single lesion
Well-demarcated unilocular or multilocular lesions or ill defined

(histologically: multinucleated giant cells)
Nondontogenic Tumors

What are the medical and surgical tx of central giant cell granuloma?
Closely resembles brown tumor and hyperparathyroidism should be ruled out in all cases
Medical: intralesional steroids, calcitonin, interferon
Surgical: aggressive curettage (usually treated surgically)
Nondontogenic Tumors

What are the clinical features of Langerhans cell histiocytosis?
Most common in CHILDREN
Males > females
Dull pain common
Nondontogenic Tumors

What are the radiographical features of Langerhans cell histiocytosis?
Radiolucent
Single or multiple lesions
Poorly defined
Teeth appear to be "floating in air"
Radiolucent
Single or multiple lesions
Poorly defined
Teeth appear to be "floating in air"
Nondontogenic Tumors

What are the tx options for Langerhans cell histiocytosis?
Radiation or chemotherapy
(poor prognosis)
Nondontogenic Tumors

What are the clinical features of cherubism?
Autosomal dominant
Most common during 2-5yo, can enlarge with growth and become stable by puberty
Painless, bilateral cheek swelling due to expansion of posterior mandible
Nondontogenic Tumors

What are the radiographical features of cherubism?
Radiolucent
Multiple lesions
Upper and lower jaws involved
(Histo: vascualr fibrous tissue containing giant cells)
Radiolucent
Multiple lesions
Upper and lower jaws involved
(Histo: vascualr fibrous tissue containing giant cells)
Nondontogenic Tumors

What is the tx of cherubism?
Observation vs surgical excision depending on sx severity
Nondontogenic Tumors

What are the clinical features of Paget Dz?
Male predominance
More common in Caucasions than African Americans
Usually occurs after 50yo
Chronic, slowly progressive
Can have cranial neuropathies if foramina are involved
Nondontogenic Tumors

What is the tx for Paget Dz?
Bisphosphonates
Calcitonin (slows bone turnover)
What are the clinical features of osteomyelitis of the jaw?
More common in mandible than maxilla
Fever, leukocytosis, swelling, lymphadenopathy
What are the clinical features of osteoradionecrosis of the jaw?
Complication from head & neck radiation, leaving bone hypocellular and hypoxic
Can be very painful
What are the tx for osteoradionecrosis of the jaw?
If mild, good oral hygiene, hyperbacric oxygen therapy, debridement as needed.

If severe, may require surgical resection with vascularized flap reconstruction
What are the clinical features of bisphosphonate-related osteonecrosis of the jaw (BRONJ)?
Occurs in pts undergoing dental procedures after receiving PO/IV bisphosphonate therapy
No hx of radiation therapy
Can be very painful
Occurs in pts undergoing dental procedures after receiving PO/IV bisphosphonate therapy
No hx of radiation therapy
Can be very painful