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21 Cards in this Set
- Front
- Back
|
Co
|
SFD / Vd
|
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LD
|
CoVd / SF
|
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CrCl
|
(140 x age x IBW) / (72 x SCr) = ml/min
=> 0.85 FM |
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IBW
|
Males: IBW = 50 kg + 2.3 kg for each inch over 5 feet.
Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet. |
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Ke
(2) |
Cl / Vd
or lnCt-lnCo / t |
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t
|
lnCt-lnCo /.ke
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peak (single dose)
|
SFD / Vd
|
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peak (mult dose)
|
SFD/Vd x trough
|
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Cpss avg
|
(SFD/T) / Cl
|
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Cp (nonsteady mult dose)
|
Cpss x (1-e^-kt)
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Cp (nonsteady single dose)
|
SFD / Vd
|
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Cpss(t)
|
peak*e^-kt / 1-e^-ktau
|
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% remaining
|
trough = peak(e-kt)
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% lost
|
trough accumulation = 1-e^-ktau
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intermittent bolus ss peak
|
Co = SFD/Vd
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intermittent short infusion ss peak
|
[(SFD/tin)(1-e^-ktau)] / Cl
|
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intermittent eq algorithm
|
yes = p+t
bolus: t50 >> tin .............(<10%loss) short infusion: t50 not >> tin |
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Vd (single dose)
|
SFD / Cpeak (or Co)
|
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Vd (mult dose) bolus
|
.
|
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|
Vd (mult dose) bolus
|
a
|
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Vd (mult dose) short infusion
|
a
|
