Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key


Play button


Play button




Click to flip

20 Cards in this Set

  • Front
  • Back
the study of the factors influencing the bioavailability of a drug in man and animal and the use of this information to optimize the pharmacological and therapeutic activity of drug products.
the study of the kinetics of absorption, distribution, metabolism, and excretion of drugs and their corresponding pharmacologic, therapeutic, or toxic responses.
the process by which a drug is transferred from the site of administration to the site of measurement.
the process of reversible drug transfer to and from the site of measurement
the irreversible loss of drug in a chemically unchanged form.
the process of conversion of one chemical species into another
The irreversible loss of drug from the site of measurement
Onset of action
the time at which the administered drug reaches the therapeutic range or begins to produce the effect
Termination of Action
The time at which the drug concentration in the plasma falls below the minimum effective concentration and stops producing the pharmacologic effect.
Therapeutic Range
the plasma or serum concentration range within which the drug is most likely to produce the therapeutic effect
Duration of Action
the time span beginning from the onset of action up to the termination of action
Passive Diffusion
a process by which a drug molecule moves from an area of high concentration to an area of low concentration due to a concentration gradient. The membrane plays a passive role.
Elimination half-life
The time at which the amount and/or concentration of drug in the body becomes 50% of the previous or initial concentration and or amount as soon as equilibrium is reached following the administration of a dose
Apparent Volume of Distribution
A proportionality constant whose sole purpose is to relate the plasma concentration with the amount of drug in the body at that time.
Linear Pharmacokinetics
A directly proportional relationship observed between the concentration and/or amount of drug and the administered dose of the drug.
Renal Clearance
The drug or the fraction thereof that is removed from the blood by the process of renal extraction
a proportionality constant describing the relationship between a substance's rate of elimination at a time and its corresponding concentration in an appropriate fluid at a time
Systemic Clearance
A proportionality constant that relates the rate of drug elimination to the plasma or serum concentration at that time.
Metabolic Clearance
The drug or fraction thereof that is removed from the blood by the process of metabolism.
Hepatic Clearance
the drug or fraction thereof that is removed from the blood by the process of metabolism.