Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
SubQ level; found in mediastinum, retroperitoneum, bowel wall; encapsulated, compsed of mature adipose tissue
|
Lipoma
|
|
2nd MC sarc. in adults; deep soft tissue; thigh, retoperitoneum; lipoblasts in different grades of differentiation; poorly differentiated tumors; chromosomal abnormalities: translocation and ring chromosomes identified
|
Liposarcoma
|
|
Mobile, well defined nodule in subQ tissues; mainly limbs; similar to fibroblasts, myofibroblasts, histiocytes; aka dermatofibromas
|
Benign Fibrous Histiocytoma
|
|
Extremities, ab. cavity, retroperitoneum + other sites; Lobulated, fleshy, infiltrating tumors w/ areas of hemorrhaging and necrosis; Histo: pleomorphic anaplastic spindle cells; storiform pattern w/ tumor giant cells and abnormal mitoses; metastesis is mainly through the blood to the lungs
|
Malignant Fibrous Histiocytoma (aka Pleomorphic Spindle Cell Carcinoma)
|
|
around teeth, in ovaries; well-defined gray masses; mature fibrous tissue
|
Fibroma
|
|
deep soft tissue; thigh; gray soft, fish-flesh infiltrating large masses w/ spindle cell growth w/ anaplasia and other features of malignancy; Herringbone pattern
|
Fibrosarcoma
|
|
rare, benign tumor of skel. musc; mature skel musc.; tongue, heart, tuberous sclerosis (mutationsin chroms. 9 or 16; benign tumors in the brain, heart, kidney, retina, and skin; seizures, mental retardation, s/s of other lesions)
|
Rhabdomyoma
|
|
Rhabdomyomas in the brain present as
|
Cortical tubers and subependymal hamartomas
|
|
MC soft tissue sarc. in children and young adults; immunohistochemical evidence of skel. musc. (biomarkers: actin, desmin, and myogenin)
|
Rhabdosarcoma
|
|
head and neck (orbit, nasophar., mid. ear) also in retoperitoneum, UG tract; sheets of small round cells
|
Embryonal Rhabdosarcoma
|
|
GU, biliary, URT; young children; polypoid, soft, grape-like appearance; undifferentiated rhabdosarcoma in myxoid tissue
|
Botryoid Rhabdosarcoma
|
|
Occur in extremities; undifferentiated rhabdomyoblasts in alveolar or pseudoglandular arrangement
|
Alveolar Rhabdosarcoma
|
|
Adult >45 y/o; mostly mm. of lower limbs; Large, atypical tumor cells, resemble pleomorphic spindle cells; highly malignant, but respond to chemo
|
Pleomorphic Rhabdosarcoma
|
|
Diabetics, alcoholics, and epileptics, APC gene mutation carriers, and those with familial adenomatous polyposis have an increased incidence of
|
Fibromatosis
|
|
Usually 2ndary to trauma, reactive cell prolif.; adults; small masses 1ly in extremities showing rapid growth; fibroblasts in loose myxoid backgroiund; enlarged nuclei, mitosis, NO ANAPHASE features; recurrence after excision is UNcommon
|
Nodular Fasciitis
|
|
Circumscribed, non-encapsulated mass w/in muscle, ususally extremities (quads); proliferated bibroblasts in myxoid stroma, associated w/ cartilage and bone formation; Usually the result of trauma, and areas of hemorrhages may also be present
|
Traumatic Myositis Ossificans
|
|
Low grade fibrosarcoma, usually locally invasive; DOES NOT METASTASIZE
|
Fibromatosis (Desmoid tumor/Aggressive Fibromatosis)
|
|
affects mothers in the perinatal period
|
Abdominal Fibromatosis
|
|
Which type of Fibromatosis affects Men and Women equally?
|
Extra-abdominal Fibromatosis
|
|
may be associated with Gardner's syndrome (=familial adenomatous polyposis, multiple osteomas, desmoid tumors)
|
Intra-abdominal Fibromatosis
|
|
Characteristics of fibromatosis
|
invades surrounding tissues, non-encapsulated exuberant fibroproliferative lesions
|
|
Presentation of fibromatosis
|
fibrous overgrowth infiltrates masses in ant. ab. wall (mainly in females), neck, shoulder ares, and pelvic girdle area
|
|
Gross appearance of Fibromatosis
|
White, sarcoma-like tumor
|
|
Histological appearance of Fibromatosis
|
bands of fibrocytes and collagenous tissue
|
|
Dapuytren Contracture
|
a special form of fibromatosis found on palms of hands
|
|
Peyronie Disease
|
Special form of fibromatosis found on the penis
|