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80 Cards in this Set
- Front
- Back
What drugs are Ototoxic... Auditory? |
Loops (Ethacrynic Acid > Furosemide) |
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What drugs are Ototoxic... Vestibular? |
Minocycline |
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What drugs are Ototoxic Auditory and Vestibular? |
Aminoglycosides |
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What drugs are Ototoxic causing Tinnitus? |
Quinidine/Quinine (cinchonism) |
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What drugs are nephrotoxic? |
Vancomycin |
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What drug causes causes SIADH? |
Carbamazepine |
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What drug causes Nephrogenic DI? |
Lithium |
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What drug causes hemorrhagic cystitis? |
Cylcophosphamide |
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How do you prevent hemorrhagic cystitis w/ cyclophosphamide? |
MESNA |
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How do you minimize nephrotoxicity from Cisplatin? |
Amifostine |
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What are the hepatotoxic drugs? |
AMIODARONE |
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What do you give to OD w/ ACETAMINOPHEN? |
Acetylcysteine |
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What drugs cause Blood dyscrasias? |
Carbamazepine |
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What drug causes Aplastic Anemia? |
Felbamate |
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What drug causes agranulocytosis? |
Clozapine |
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What drug causes aplastic anemia and is dose dependent and dose independent? |
Chloramphenicol |
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What HIV medication causes Blood dyscrasias (anemia/bone marrow suppresion)? |
Zidovudine |
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What anticoagulant produces thrombocytopenia? |
Heparin |
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What drug causes thrombotic thromocytopenia, purpura or TPP? |
Ticlopidine |
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Most Cancer chemotherapeutic drugs cause? |
Blood Dyscrasias |
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What drugs cause pancreatitis? |
Valproic Acid |
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What drug used for seizures causes pancreatitis? |
Valproic Acid |
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What drug used for HIV cause pancreatitis? |
Didanosine |
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What NSAID causes pancreatitis? |
Sulindac |
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What drug used for ALL causes pancreatitis? |
Asparaginase |
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What drugs produce gingival hyperplasia? |
Phenytoin |
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What drugs cause SLE in SLOW acetylators? |
Hydralazine |
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Drugs w/ problems with Atypical Pseudocholinesterase? |
Succinylcholine (prolongs the activity) |
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What drug causes malignant hyperthermia? |
Halothane/SUX |
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What drug causes Hemolytic Anemia in G6PD deficiency? |
Sulfonamide |
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What drugs cause disulfiram like reaction? |
Metronidazole |
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What drug (combination) causes Serotonin Sx? |
MAOIs, TCAs, SSRIs, Meperidine |
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What drug causes acute hypertensive crisis? |
Non-Selective MAOIs + Tyramine |
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What are the non-selective MAOIs? |
Phenelzine |
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What contains Tyramine? |
Aged Cheese |
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What DDI (drug-drug interaction) causes decrease in B.P. and possible death? |
Sildenafil + Nitroglycerin |
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What two drugs in anti-cancer therapy you should never mix? |
6-MP (Azathioprine) + Allopurinol |
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DOC for Borrelia? |
Doxycicline |
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DOC for Ricketssia? |
Doxycycline |
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DOC for T. pallidum? |
Penicillin G |
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DOC for gonorrhea? |
Ceftriaxone |
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DOC for Atypicals (Chlamydia, Mycoplasma)? |
Doxycicline or |
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DOC listeria? |
Ampicillin |
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DOC Legionella? |
Macrolide |
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DOC Step (Group A)? |
Pen G [V] |
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DOC C. difficile? |
Metronidazole |
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DOC enterococcus? |
Penicillin + AG (Aminoglucoside) |
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DOC P. areuginosa? |
Ticarcillin + AG |
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DOC for T. pallidum but penicillin allergy? |
Doxycicline |
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DOC N. gonorreah but Penicillin Allergy? |
Floxacin |
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DOC for Listeria but penicillin allergy? |
TMP-SMX |
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DOC Strep (Group A) but penicillin allergy? |
Macrolide |
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DOC enterococcus but penicillin allergy? |
Vacomycin + AG |
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DOC P. areuginosa but penicillin allergy? |
Aztreonam |
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DOC Borrelia in Pregnancy or Child? |
Amoxicillin |
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DOC Ricketssia in Pregnancy or Child? |
Chloramphenicol |
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DOC N. gonorrhea in Pregnancy or Child? |
Ceftriaxone |
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DOC atypicals [chlamydia, Mycoplasma] in Pregnancy or Child? |
Macrolide |
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DOC P. areuginosa w penicillin allergy? |
Aztreonam, AG, Floxacin |
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DOC for Borelia for a prenant woman? |
Amoxicillin |
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DOC N. gonorrhea for a prenant woman? |
Ceftriaxone |
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DOC Atypicals [Chlamydia, Mycoplasma] for a prenant woman? |
Macrolide |
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DOC for Borrelia in Children? |
Amoxicillin |
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DOC N. gonorrhea in Children? |
Ceftriaxone |
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DOC Atypicals in Children? |
Macrolides |
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What is the Serotonin Sx? |
Hyperthermia |
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What causes Serotonin Sx in w/ Meperidine? |
Combination w/ MAOIs, TCAs |
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How do protease inhibitors work? |
Inhibit Aspartate Protease |
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Name two protein inhibitors? |
Indinavir |
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What happens to Uric Acid at high does Aspirin? |
UA stays in the lumen and is peed out = uricosuric |
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What happens to Uric acid w/ low dose Aspirin? |
Transport of UA (Uric Acid) is blocked from the blood to the lumen so it causes hyperuricemia |
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What drug protects patient from nephrotoxicity taking cisplatin? |
Amifostine |
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What drug prevents cardiotoxicity w/ Doxorubicin? |
Dexrazoxane |
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What drug prevents toxicity to epithelial, GI and bone marrow in Methotrexate high dose anti-cancer tx? |
Leucovorin |
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Where does Aspirin work? |
COX-1 |
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Where does abcximab work? |
GP IIB/IIIA receptor on platelets. Can't join together |
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Where does ticlopidine work? (Clopidrogel) |
Blocks ADP release |
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Where does propilthioracil and Methimazole work? |
Peroxidase in thyroid synthessis |
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Where does Iodide (high dose) work? |
blocks release of proteolytic T3 ---> T4 |
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Where does Propilthioracil and Propanolol work? |
inhibit deiodinase (liver) conversion of T4 to T3 |