Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/80

Click to flip

80 Cards in this Set

  • Front
  • Back
What drugs are Ototoxic... Auditory?
Loops (Ethacrynic Acid > Furosemide)
VANCOMYCIN
Macrolides
Cisplatin
What drugs are Ototoxic... Vestibular?
Minocycline
What drugs are Ototoxic Auditory and Vestibular?
Aminoglycosides
What drugs are Ototoxic causing Tinnitus?
Quinidine/Quinine (cinchonism)
ASA (salicylism)
What drugs are nephrotoxic?
Vancomycin
Aminoglycosides
Amphothericin B
Foscarnet (hypercalcemia)
Cisplatin (minimized w/ Amifestine)
Cyclosporine
What drug causes causes SIADH?
Carbamazepine
Chlorpropamide
What drug causes Nephrogenic DI?
Lithium
Demeclocycline
What drug causes hemorrhagic cystitis?
Cylcophosphamide
How do you prevent hemorrhagic cystitis w/ cyclophosphamide?
MESNA
How do you minimize nephrotoxicity from Cisplatin?
Amifostine
What are the hepatotoxic drugs?
AMIODARONE
STATINS
VALPROIC ACID (hepatitis)
Felbamate
Tolcapone
TETRACYCLINE (in pregnancy)
RIPE TB therapy (Rifampin, Isoniazid, Pyrazinamide)
ACETAMINOPHEN
What do you give to OD w/ ACETAMINOPHEN?
Acetylcysteine
What drugs cause Blood dyscrasias?
Carbamazepine
What drug causes Aplastic Anemia?
Felbamate
What drug causes agranulocytosis?
Clozapine
What drug causes aplastic anemia and is dose dependent and dose independent?
Chloramphenicol
What HIV medication causes Blood dyscrasias (anemia/bone marrow suppresion)?
Zidovudine
What anticoagulant produces thrombocytopenia?
Heparin
What drug causes thrombotic thromocytopenia, purpura or TPP?
Ticlopidine
Most Cancer chemotherapeutic drugs cause?
Blood Dyscrasias
What drugs cause pancreatitis?
Valproic Acid
Didanosine/Zalcitabine
Sulindac
Asparaginase
What drug used for seizures causes pancreatitis?
Valproic Acid
What drug used for HIV cause pancreatitis?
Didanosine
Zalcitabine
What NSAID causes pancreatitis?
Sulindac
What drug used for ALL causes pancreatitis?
Asparaginase
What drugs produce gingival hyperplasia?
Phenytoin
Nifedipine
Cyclosporine
What drugs cause SLE in SLOW acetylators?
Hydralazine
Isoniazid
Procainamide
Drugs w/ problems with Atypical Pseudocholinesterase?
Succinylcholine (prolongs the activity)
What drug causes malignant hyperthermia?
Halothane/SUX
What drug causes Hemolytic Anemia in G6PD deficiency?
Sulfonamide
Primaquine
Quinidine
What drugs cause disulfiram like reaction?
Metronidazole
Chlorpropamide
Griseofulvin
Cefamandole
Cefotetan
Cefoperazone
What drug (combination) causes Serotonin Sx?
MAOIs, TCAs, SSRIs, Meperidine
What drug causes acute hypertensive crisis?
Non-Selective MAOIs + Tyramine
What are the non-selective MAOIs?
Phenelzine
Trancylpromine
What contains Tyramine?
Aged Cheese
Red Wine
What DDI (drug-drug interaction) causes decrease in B.P. and possible death?
Sildenafil + Nitroglycerin
What two drugs in anti-cancer therapy you should never mix?
6-MP (Azathioprine) + Allopurinol
precipitate gout
DOC for Borrelia?
Doxycicline
DOC for Ricketssia?
Doxycycline
DOC for T. pallidum?
Penicillin G
DOC for gonorrhea?
Ceftriaxone
"Floxacins"
DOC for Atypicals (Chlamydia, Mycoplasma)?
Doxycicline or
Macrolide
DOC listeria?
Ampicillin
DOC Legionella?
Macrolide
DOC Step (Group A)?
Pen G [V]
DOC C. difficile?
Metronidazole
or Vancomycin
DOC enterococcus?
Penicillin + AG (Aminoglucoside)
DOC P. areuginosa?
Ticarcillin + AG
DOC for T. pallidum but penicillin allergy?
Doxycicline
DOC N. gonorreah but Penicillin Allergy?
Floxacin
DOC for Listeria but penicillin allergy?
TMP-SMX
DOC Strep (Group A) but penicillin allergy?
Macrolide
DOC enterococcus but penicillin allergy?
Vacomycin + AG
DOC P. areuginosa but penicillin allergy?
Aztreonam
DOC Borrelia in Pregnancy or Child?
Amoxicillin
DOC Ricketssia in Pregnancy or Child?
Chloramphenicol
DOC N. gonorrhea in Pregnancy or Child?
Ceftriaxone
DOC atypicals [chlamydia, Mycoplasma] in Pregnancy or Child?
Macrolide
DOC P. areuginosa w penicillin allergy?
Aztreonam, AG, Floxacin
DOC for Borelia for a prenant woman?
Amoxicillin
DOC N. gonorrhea for a prenant woman?
Ceftriaxone
DOC Atypicals [Chlamydia, Mycoplasma] for a prenant woman?
Macrolide
DOC for Borrelia in Children?
Amoxicillin
DOC N. gonorrhea in Children?
Ceftriaxone
DOC Atypicals in Children?
Macrolides
What is the Serotonin Sx?
Hyperthermia
Rigidity
Autonomic Instability
Myoclonus

Kind of like when having sex!!!
What causes Serotonin Sx in w/ Meperidine?
Combination w/ MAOIs, TCAs
but it is a metabolite called normeperidine that acts like SSRI
How do protease inhibitors work?
Inhibit Aspartate Protease
Name two protein inhibitors?
Indinavir
RitonAVIR

gp120
gp41
What happens to Uric Acid at high does Aspirin?
UA stays in the lumen and is peed out = uricosuric
What happens to Uric acid w/ low dose Aspirin?
Transport of UA (Uric Acid) is blocked from the blood to the lumen so it causes hyperuricemia
Aspirin (low dose) blocks secretion of Uric Acid
What drug protects patient from nephrotoxicity taking cisplatin?
Amifostine
What drug prevents cardiotoxicity w/ Doxorubicin?
Dexrazoxane
What drug prevents toxicity to epithelial, GI and bone marrow in Methotrexate high dose anti-cancer tx?
Leucovorin
restores purines
Where does Aspirin work?
COX-1
Cycloxygenase 1
Where does abcximab work?
GP IIB/IIIA receptor on platelets. Can't join together
Where does ticlopidine work? (Clopidrogel)
Blocks ADP release
Where does propilthioracil and Methimazole work?
Peroxidase in thyroid synthessis
Where does Iodide (high dose) work?
blocks release of proteolytic T3 ---> T4
Where does Propilthioracil and Propanolol work?
inhibit deiodinase (liver) conversion of T4 to T3