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36 Cards in this Set

  • Front
  • Back
What is the nicotinic cholinomemetic?
Nicotine
What are the muscarinic cholinomimetics?
bethanechol, methacholine, pilocarpine
What are the Nn cholinoceptor Blockers?
hexamethonium, mecamylamine
What are the Nm cholinoceptor blockers?
tubocurarine, atracurium, succinylcholine
What are the muscarinic cholinoceptor blockers?
atropine, benztropine, glycopyrrolate, scopolamine
What are the clinical uses of bethanechol?
ilius (post op/neurogenic), urinary retention
What are the clinical uses of methacholine?
to diagnose bronchial hyper-reactivity
What are the clinical uses of pilocarpine?
put on eye to reduce glaucome and to treat drymouth (xerostomia)
What are the indirect acting cholinomimetics?
edrophonium, physostigmine, neostigmine and pyridostigmine, Donepezil and tacrine, organophosphates
What is unique about edrophonium?
Very short acting and only used to diagnose myasthenia gravis.
Unique about physostigmine?
can cross Blood Brain Barrier because it is a tertiary amine (tert. amines are about the be charged or uncharged)

used for glaucoma and Atropine Overdose
What distinguishes neostigmine and pyridostigmine from physostigmine?
They are charged (b/c quaternary amines) and thus do not cross the Blood Brain barrier and thus are the drugs used for the majority of uses (myasthenia, urinary retention, reversal of non-depolarizing NM blockers)
What drugs should be given in an organophosphate overdose?
atropine and prylodoxine
What is the management of an Atropine overdose
symptomatic and physostigmine
What are the MAO inhibitors?
Phenylzine, Tranylcypromine
Which drugs act on the mobile pool?
amphetamine, ephedrine, tyramine
Which drugs block the reuptake of NE?
cocaine
Which drugs stimulate the prejunctional alpha receptors?
Clonodine, Alpha-Methyldopa
Which drugs inhibit the granular uptake of NE?
reserpine
Which drugs inhibit the granular release of NE?
Guanethidine
Which drugs are Alpha1 agonists?
phenylephrine and methoxamine
Which drugs are Alpha2 agonists?
clonidine and Alpha-Methyldopa
Which drugs are both Beta1 and Beta2 agonists?
isoproterenol
Which drugs are both Beta1 and Beta2, but primarity Beta1 agonists?
dobutamine
Which drugs are Beta2 agonists?
metaproterenol, albuterol, and terbutaline are for asthma........ and rotodrine for premature labor
Which drugs are Alpha1, Alpha2, and Beta1 agonists?
Norepinephrine
Which drugs are Alpha1, Alpha2, Beta1, and Beta2 agonists?
Epinephrine
Which drugs are Alpha1 and Alpha2 antagonists?
phentolamine and phenoxybenzamine
Which drugs are Alpha1 antagonists?
Prazocin and the rest of the -ocin family
Which drugs are Beta1 nad Beta2 antagonists?
Propranolol
Whiich drugs are Beta1 Antagonists?
"AMA" - Acebutolol, Atenolol, nad Metoprolol
Which drugs are Beta1 Partial Agonists/Antagonists?
"PA" - Pindolol and Acebutolol
Which drugs Beta Blockers with no CNS entry?
Atenolol and Nadolol
Which Beta Blockers have a long half life?
Carvdilol and Nadolol
Which drugs have combined Alpha and Beta Blocking activity?
Carvedilol and Labetalol
Which drugs are used to treat glaucoma?
-Muscarinic agonists, Alpha2 agonists, and beta antagonists to decrease NE effect........Acetazolamide (Carbonic anhydrase inhibitor) b/c the decrease HCO3 will decrease aqueous humor production and Latanoprost which is a PGF analog which will increase outflow