Jz Uhcl Cellular Physiology Final Exam 4 2/2

Front 1

1) Actin is *** wide.
2) Intermediate filaments are *** wide.
3) Microtubules are *** wide.

Back 1

1) 7 nm
2) 10 nm
3) 25 nm

Front 2

*** AKA actin filaments

Back 2

Microfilaments

Front 3

Eukaryotic cells contain these types of cytoskeletal filaments.
1)
2)
3)

Back 3

1) microfilaments
2) intermediate filaments
3) microtubules

Front 4

The *** filament subunit changes more.

Back 4

β

Front 5

The *** filament subunit has a positive charge.

Back 5

β

Front 6

The *** filament subunit has a negative charge.

Back 6

α

Front 7

--- G-Protein Linked Receptor ---
1) # transmembrane segments
2) AKA ***

Back 7

1) 7
2) serpentine

Front 8

Insulin is a ***

Back 8

TKR

Front 9

--- G-Protein ---
1) *** with # subunits
2) called ***, ***, and ***.

Back 9

1) Trimeric --- 7
2) α, β, and γ

Front 10

--- G-Protein ---
1) *** subunit decouples & pops da pup.
2) *** binds the first subunit which is ***.

Back 10

1) γ
2) GDP --- α

Front 11

GPCR?

Back 11

G Protein-Coupled Receptor

Front 12

--- GPCR ---
1) Inactive GPCR contains ***.

Back 12

1) GDP

Front 13

1) Active GPCR contains ***.
2) and an activated *** subunit and *** complex.
3) The *** subunit does all sorts of tricks.

Back 13

1) GTP
2) α --- βγ
3) α

Front 14

--- ECM Components ---
1) M***
2) F***b***
3) C*** Fiber
4) E*** Fiber
5) M*** C***

Back 14

1) Macrophage
2) Fibroblast
3) Collagen Fiber
4) Elastic Fiber
5) Mast Cell

Front 15

GAG?

Back 15

GlycosAminoGlycans

Front 16

1) GAGs(GlycosAminoGlycans) form the '*** ***' found in the ECM.
2) Composed of r*** d*** pattern.

Back 16

1) styrofoam cushioning
2) repeating disaccharide

Front 17

Hyaluronan is a ***.

Back 17

GAG
GlycosAminoGlycan

Front 18

An example of a GAG protein is....

Back 18

hyaluronan

Front 19

1) *** is formed when highly glycosylated
2) glycoprotein is linked to a ***.

Back 19

1) proteoglycan
2) GAG

Front 20

--- *** *** ---
Contains hyaluronan
heratan sulfate
chondroitin sulfate
and link/core proteins.

Back 20

aggrecan aggregate

Front 21

--- Aggrecan Aggregate ---
1) *** molecule
2) Keratan ***
3) Chondroitin ***
4) L*** protein
5) C*** protein(aggrecan)

Back 21

1) Hyaluronan
2) sulfate
3) sulfate
4) Link
5) Core

Front 22

The core protein is also known as the ***.

Back 22

aggrecan

Front 23

--- Collagen Molecule ---
1) Structure is always *** ***.
2) Repeating units are...

Back 23

1) triple trimeric
2) glycine, x, y

Front 24

1) *** molecule is always triple trimeric
2) w/repeating units of ***, x, and y .

Back 24

1) Collagen
2) glycine

Front 25

--- Embryonic Chick Skin ---
Connective tissue contains *** surrounded by collagen ***.

Back 25

Fibroblasts --- fibrils

Front 26

--- Embryonic Chick Skin ---
Connective tissue contains fibroblasts surrounded by *** ***.

Back 26

collagen fibrils

Front 27

1) Vitamin C is required for the *** of lysine and of proline.
2) These two become *** and ***
3) and are necessary for proper *** cross-linking.

Back 27

1) hydroxylation
2) hydroxylysine and hydroxyproline
3) collagen

Front 28

*** and *** are necessary for proper collagen cross-linking.

Back 28

Hydroxylysine and hydroxyproline

Front 29

A lack of Vitamin C can cause ***.

Back 29

scurvy

Front 30

Vitamin C is required for the hydroxylation of *** and of ***.

Back 30

lysine --- proline

Front 31

--- Protein Name ---
Pro means ***.

Back 31

inactive

Front 32

--- Formation of Collagen Fiber ---
1) Synthesis of ***-*** ***
2) Hydroxylation of selected *** and ***
3) Glycosylation of selected ***
4) ***(noun) ***(verb) of three pro-α chains
5) Procollagen t***-h*** formation
6) S***
7) Cleavage of p***
8) Self-assembly into ***
9) Aggregation of collagen *** to form a collagen ***

Back 32

1) pro-α chain
2) prolines --- lysines
3) hydroxyLysines
4) Self assembly
5) triple-helix
6) Secretion
7) propeptides
8) fibril
9) fibrils --- fiber

Front 33

--- Formation of Collagen Fiber ---
1) S*** of pro-α chain
2) *** of selected prolines and lysines
3) *** of selected hydroxyLysines
4) ***-*** of three pro-α chains
5) *** triple-helix formation
6) Secretion
7) *** of propeptides
8) ***-*** into fibril
9) *** of *** fibrils to form a *** fiber

Back 33

1) Synthesis
2) Hydroxylation
3) Glycosylation
4) Self-assembly
5) Procollagen
6) Secretion
7) Cleavage
8) Self-assembly
9) Aggregation --- collagen --- collagen

Front 34

--- Formation of Collagen Fiber ---
1) Procollagen triple-helix is synthesized in the....
2) It is composed of...

Back 34

1) ER/Golgi compartment
2) 3 pro-α chains

Front 35

--- Formation of Collagen Fiber ---
1) *** t***-*** is secreted in secretory vesicles into the ECM.

Back 35

1) Procollagen triple-helix

Front 36

--- Formation of Collagen Fiber ---
1) Procollagen molecule is ***
2) by s*** p***
3) into *** molecule
4) which form the c*** ***
5) which is # to # *** wide.

Back 36

1) cleaved
2) signal peptidase
3) collagen
4) collagen fibril
5) 10 - 300 nm

Front 37

--- Cell Cycle ---
*** is the quiescent phase.

Back 37

G0

Front 38

--- Cell Cycle ---
G0 is the *** phase.

Back 38

quiescent

Front 39

--- Cell Cycle ---
1) Cell enters cell cycle by going into *** phase.
2) Before M/Mitosis phase is *** phase.

Back 39

1) S
2) G2

Front 40

Name the three types of cell junctions.
1) O*** junctions
2) A*** junctions
3) C*** junctions

Back 40

1) Occluding
2) Anchoring
3) Communicating

Front 41

*** Junctions are only found in vertebrates.

Back 41

Tight

Front 42

Claudin and occludin are *** *** proteins.

Back 42

tight junction

Front 43

Intracellular anchor proteins and transmembrane adhesion proteins form *** ***.

Back 43

anchoring junctions

Front 44

C*** and o*** are tight junction proteins.

Back 44

Claudin
occludin

Front 45

--- Anchoring Junctions ---
Composed of...
1) I*** a** proteins
2) t*** a** proteins.

Back 45

1) Intracellular anchor
2) transmembrane adhesion

Front 46

Communicating Junctions are composed of...
1) *** S***
2) *** J***

Back 46

1) Chemical Synapses
2) Gap Junctions

Front 47

*** *** are composed of...
1) Chemical Synapses
2) Gap Junctions

Back 47

Communicating Junctions

Front 48

--- Gap Junctions ---
***, ***, and e*** s*** controls opening/closing

Back 48

pH --- Ca++ --- extracellular signals

Front 49

--- Gap Junctions ---
1) *** Ca++ causes closure.
2) *** pH causes closure.
3) *** is an extracellular signals causing closure.

Back 49

1) Increased
2) Decreased
3) Dopamine

Front 50

--- Gap Junctions ---
1) Decreased *** causes closure.
2) Increased *** causes closure.
3) Dopamine is an extracellular signal causing ***.

Back 50

1) pH
2) Ca++
3) closure

Front 51

--- Gap Junctions ---
Max MW that can pass through is # ***.

Back 51

1kDa

Front 52

*** form open channels between cells.

Back 52

Connexons

Front 53

--- Gap Junction Channel ---
1) *** is an assembly of six
2) *** proteins forming open channel.

Back 53

1) Connexon
2) connexin