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28 Cards in this Set
- Front
- Back
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Leukocyte
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Derived from multipotent cells in the bone marrow, contains all the white blood cells.
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Lymphocyte
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T-cells, B-cells, NK-cells
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B-cell develops into...
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Plasmacell
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T-cell matures into...
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Cytotoxic T-cell
Helper T-cell regulatory T-cell |
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Activated function of Macrophage
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Phagocytosis, activation of bactericidal functions, Antigen presentation
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Activated function of Dendritic cell
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Antigen uptake in peripheral sites, Antige presentation
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Activated function of Neutrophil
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Phagocytosis and activation of bactericidal mechanisms
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Activated function of Eosinophils
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Killing of antibody-coated parasites
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Activated function of Basophil
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unknown
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Activated function of Mast cell
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Release of granules containing histamine and active agents.
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Cytokine (general)
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Cytokine is a general name for any protein taht is secreted by cells and effects the behavior of nearby cells bearing appropriate receptors.
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Chemokines
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Chemokines are secreted proteins that attract cells bearing chemokine receptors.
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Inflammatory cells
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Cells being recruited into inflamed tissue: Macrophages, neutrophils.
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PAMPs
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Pathogen-associated molecular patterns; molecular structures present on many microorganisms but not on the body's own cells.
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PRRs
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Pattern recognition receptor; receptors that recognize PAMPs.
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B-cell antigen receptors are adapted to recognize which kind of antigens?
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surface antigens of pathogens living outside cells
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T-cell antigen receptors are adapted to recognize which kind of antigens?
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antigens that have been produced by breakdown of proteins. The antigen has to be presented on a MHC protein.
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MHC
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Major histocompatibility complex
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What does a naive lymphocyte need to be activated?
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Specific antigen and Co-stimulatory molecules, whose expression is regulated by innate immunity
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Lymphoblast
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Naïve Lymphocyte after activation by a antigen presenting cell.
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Where are Antibodies found?
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Blood, plasma extracellular fluids
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Neutralization by Antibodies?
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Binding to pathogens or their products and thereby blocking their access to cells
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Opsonization by antibodies?
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Coating of pathogens and foreign particles to induce phagocytosis by macrophages
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Complement activation by Antibodies?
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The constant region of the AB helps that the first protein of the complement system is able to bind.
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Main classes of T-lymphocytes
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CD4 and CD8
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Which T-cell carries CD8?
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Cytotoxic T-cells
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A naïve CD8 T cell matures into…?
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A cytotoxic T cell
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A naïve CD4 T cell matures into…?
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Two major groups: Th1 and Th2
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