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18 Cards in this Set
- Front
- Back
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Calculate Loading Dose
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LD = Vd x Css
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Calculate Maintenance dose
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MD = Cl x Css x τ
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Calculate Infusion Rate
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Ko = Cl x Css
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Equation for Volume of distribution (Vd)
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Vd = D/C
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Equation for half life
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t1/2 = 0.7/k<br>
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Equation for Clearance
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Cl = k x Vd
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Integrative equation for half life
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t1/2 = <span style="text-decoration: underline;">0.7xVd</span><br> Cl
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Atropine-like drugs (Drugs that have anticholinergic effects)
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<span style="font-weight:600; color:#0000ff;">TAQAMA:</span><br /><span style="color:#0000ff;">T</span>CA, <span style="color:#0000ff;">A</span>ntipsychotics, <span style="color:#0000ff;">Q</span>uinidine, <span style="color:#0000ff;">A</span>mantadine, <span style="color:#0000ff;">M</span>eperidine, <span style="color:#0000ff;">A</span>ntihistamines
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Drugs causing Torsades de Pointes
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Potassium channel blockers (Class III and Class IA)<br>Antipsychotics (Thioridazone)<br>TCAs
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Vessel specific vasodilators
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<span style="color:#ff0000;">Arterioles: CCB, Hydralazine, KCB </span><br><span style="color:#ffaa00;">--> reflex tachycardia & edema</span><br><span style="color:#5500ff;">Venules: Nitrates </span><br><span style="color:#ffaa00;">--> orthostatic hypotension</span><br>Both: the rest!
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Equation for Diffusion
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J ~ <span style="text-decoration: underline;">ΔP x SA x SOL</span><br> T x √MW
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Zero-order Elimination
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High doses of: <br>Phenytoin, Ethanol, Salicylates
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Symptoms of NMS
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FEVER<br><br>Fever<br>Encephalopathy<br>Vitals unstable<br>Elevated enzymes<br>Rigidity of muscles
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G-protein associated with Angiotensin II receptors
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Gq
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G-protein associated with Adenosine Receptors
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Bronchi and Blood vessels: Gq<br><br>Heart: Gi
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G-protein associated with Glucagon
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Gs
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G-protein associated with PGI2
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Gs
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B-blockers that are partial agonists (ISA)
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Acebutolol and pindolol
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