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10 Cards in this Set
- Front
- Back
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What are the cerebral effects of opioids?
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Decreased CMRO2, CBF, ICP (but < benzos and barbs), N/V d/t stimulation of CTZ
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What are the GI effects of opioids?
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Slowed gastric emptying/motility, Spasm of the sphincter of odi -> biliary colic, pain (like angina)
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When is opioid-induced sphincter of odi contraction a particularly significant problem?
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ERCP
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How is sphincter of odi spasm treated?
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Naloxone and glucagon
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What are the GU effects of opioids?
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Antidiuretic, can cause urinary retention (Mu1 vs. Kappa)
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When is pruritis most common with opioids?
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Neuraxial
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Is there a maximum dose for opioids?
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No, limited only by SEs
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What drugs cause increased ventilatory depression when combined with opioids?
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Antidepressents, Propofol, Barbiturates, Benzos
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What drugs cause CV depression when combined with opioids?
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Benzos and Inhaled agents including nitrous oxide
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What drugs cause enhanced analgesia with opioids?
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Clonidine and NSAIDS
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