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10 Cards in this Set
- Front
- Back
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Can consent be obtained after benzo administration?
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No
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Can consent be obtained after diphenhydramine administration?
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Yes
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What is an opioid?
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All drugs, natural or synthetic, with morphine-like properties that bind to opioid receptors as agonists
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What does "morphine" mean?
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Name for morpheus, God of dreams
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What are the 4 major opioid receptors?
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Mu1, Mu2, Kappa, Delta
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What does peripheral opioid receptor activation cause?
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inhibition of pre and post-synaptic response to exictatory neurotransmitters from nocioceptive neurons.
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What is the effect of opioid receptor activation in the CNS?
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Activation of a descending inhibitory pathway from the periaqueductal grey to the dorsal horn of the spinal cord
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What is the response to stimulation of the Mu1 receptor?
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Euphoria, Meiosis, Pruritis, Urinary retention
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What is the response to stimulation of the Mu2 receptor?
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Respiratory depression, sedation, bradycardia, ileus, physical dependence
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What is the response to stimulation of the Delta receptor?
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Respiratory depression, physical dependence
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