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13 Cards in this Set
- Front
- Back
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What is the MOA for Polymyxin B?
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high molecular weight peptide that injures gram negative bacteria plasma membranes
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What is the use for Polymyxin B?
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IV formulation for very resistant bugs
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What are the black box warnings for Polymyxin B?
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extreme neuro and kidney toxicity--> renal failure and seizures
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What are the three components of Neosporin?
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Polymicin B, Neomycin, and Bacitracin
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What is the use for Neosporin?
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strictly localized infections of the skin
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What are the two drugs in Polysporin?
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Polymyxin B and Bacitracin
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What is the topical agent Mupirocin (Bactroban) used for?
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S. aureus and Group A strep infections, incl MSSA and MRSA
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MOA for Mupirocin (Bactroban)
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inhibits bacterial protein synthesis
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What is Neomycin used for?
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Gram negative organism
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What is Polymyxin B used for?
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gram negative organism
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What is Gramicidin used for?
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gram positive organism
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Many topical antibiotics contain a combination of these four agents.
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Bacitadin, Gramicidin, Neomycin, and Polymyxin B
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Topical antibiotic effective against MSSA and MRSA
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Bactroban (Mupirocin)
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