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19 Cards in this Set
- Front
- Back
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Organism that causes Toxoplasmosis
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Toxoplasma gondii
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What type of organism is Toxoplasma gondii?
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obligate intracellular parasite
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What groups get severe disease>
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fetuses, newborns, immunocompromised
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How is Toxoplasmosis spread?
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through ingestion of contaminated material infected with feces from acutely infected cats
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How is Toxoplasmosis transported in the body?
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via the lymphatics and disseminated hematogenously through the body
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S/S of Toxo in immunocompetent host
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80% are asymptomatic; mono like illness with cervical lymphadenopathy, fever, malaise, night sweats, myalgias, pharyngitis
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S/S of Toxo in immunocompromised host
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Toxoplasmic encephalitis in AIDS, in non AIDS- CNS disease with visual change sin 50%, myocarditis, and pneumonitis, as well as symptoms that immunocompetent host would have
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MC manifestation of Toxoplasmosis
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Toxoplasmosis encephalitis
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S/S of congenital Toxo
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in 2/3- no S/S, ocular involvement in 15%, intracranial calcification in 10%, at birth- anemia, thrombocytopenia jaundice, microcephaly, and hydrocephalus
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Congenital Toxo is more severe if ___________.
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mom had disease early in pregnancy
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MC presentation of Congenital Toxoplasmosis.
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Chorioretinitis
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Average age onset of chorioretinitis
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4 years
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S/S of chorioretinitis
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blurred vision to vision loss; exudative bilateral retinal lesions
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S/S of Congenital Toxo
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chorioretinitis, mental retardation, seizures, visual defects, spasticity, severe neurological sequelae
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How is diagnosis of Toxo made
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demonstration of the organism in blood, body fluids, tissue, amniotic fluid
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What does ELISA indicate in Toxo?
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indicates acute infection
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If congenital disease is suspected, what is done to detect Toxo?
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amniocentesis at 20-24 weeks gestation
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Tx of Toxo in asymptomatic hosts
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none (exception--> kids under 5)
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Review the tx for Toxo (chart) in book
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too much for cards
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