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9 Cards in this Set
- Front
- Back
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Examples of systemic diseases that adversely affect the glomeruli
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DM, SLE, Sickle Cell, Amyloidosis, Alport's Syndrome, Hep C, HIV
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What is oliguria?
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urine output < 400 ml/day
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What is azotemia?
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buildup of nitrogenous wastes in blood, secondary to decreased renal function
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What are crescents?
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proliferation of cells within Bowman's capsule in response to glomerular rupture (marks severe glomerular injury)
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What are oval fat bodies?
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sloughed tubular epithelial cells that have reabsorbed some of the excess lipoproteins in urine
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Three major classes of glomerular disease.
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nephritic syndrome, nephrotic syndrome, and asymptomatic renal disease
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The damage to glomeruli is often manifested as an ____________ process.
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inflammatory
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What is one of the most helpful diagnostic techniques for finding the cause of glomerular disease?
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renal biopsy because it can detect the specific histologic pattern of injury
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What are typical clinical findings of glomerular disease that present as nephritic syndrome?
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hematuria, proteinuria, HTN, and reduced GFR
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