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31 Cards in this Set

  • Front
  • Back
CELL IS THE FUNDAMENTAL UNIT OF
ALL LIVING THINGS
The Plasma Membrane marks
THE BOUNDARY OF THE CELL.
STATE 3 FEATURES OF THE PLASMA MEMBRANE
phospholipid bi-layer
Selectively permeable
regulate the internal cellular composition
IN AN AQEUOUS ENVIRONMENT WHAT DO PHOSHOPLIPDS FORM
MICELLES
WHAT ELSE CAN PHOSPHOLIPIDS FORM

STATE 2 FEATURES OF THIS
PHOSPHOLIPIDS CAN CALSO FORM BILAYERS

WHICH HAVE HYDROPHILLIC PHOSPHATE GROUSP FACING OUTWARDS AND INWARDS


AND A HYDROPHOBIC ENVIRONMENT BETWEEN THEM
WHAT DO ALL CELLS HAVE IN COMMONG
they are either prokaryotes or eukaryotes
BACTERIA ARE WHAT TYPE OF ORGANISM

WHAT DOES THE TERM PROKARYOTE MEAN

WHAT DONT PROKARYOTES CONTAIN
Bacteria are small single-cell organisms

These are classed as prokaryotes

Prokaryote means “without a nucleus”

Prokaryotes generally do not contain organised membranous internal structures
NAME ATLEAST 6 DIFFERENT PROKARYOTE TYPES
NAME 5 THINGS THAT A PROKARYOTE MAY CONTAIN
CAPSULE
RIBOSOME
CELL WALL
NUCLEOID
FLAGELLA
PILLI
MESOOME

CAPSULE ENCASING
WHAT DO EVOLUTIONARY TREE'S INDICATE
Evolutionary tree indicating the lines of descent of cellular life on Earth
WHAT DID WE ALL DESCEND FROM ORIGINALLY
ANCESTRAL PROKARYOTE
DIFFERENCE IN eu AND PROKARYOTIC


NUCLEUS

ORGANELLES

GENOME

HISTONES

INTRONS
prokary eukaryotic
nucleus absent nucleus present
no membrane bound orgs several membran b org
1 molecule circular dna several molecules oflinear

no histones histones present

no introns in genes introns in genes present
difference in eu and prokaryotic


rna polymerase

ribosomes

translation
one rna polymerase type 3types
70s ribsome 80s ribosome

polycistronic translation monocistronic
In Eukaryotes the presence of a nucleus means what 3 things
RNA is synthesised in the nucleus

Proteins are synthesised in the cytosol

Transcription has to be completed and the RNA exported from the nucleus to the cytoplasm before translation can occur
what is the Major cell cycle difference between prokaryotes and eukaryotes
Continuous process in prokarotes
Discrete steps in Eukarotes

Eukaryote cells need to put normal functions on hold whilst the cells divide

DNA synthesis (replication) is completed before cell division can occur
what is mitosis
Mitosis, the usual form of cell division in eukaryotes

leads to the production of 2 daughter cells that are genetically identical
outline the stages of mitosis
viruses are not...

cannot.....


they are obligate.....

hijack....

can be a major
Not living cells

Cannot carry out any living functions on their own

Obligate intracellular parasites

Hijack the cell’s machinery to get themselves replicated

Can be a major cause of disease
name 4 features of the aids hiv virus
prokaryotes also have....?


examples?
viruses



T7 bacteriophage of Escherichia coli
4 features of this virus
head containing dna


neck


collar

sheath

tail fiber

base plate
what is KURU
Kuru, a neurodegenerative disease affecting the South Fore people of Papua New Guinea has been studied since the early 1900s
WHAT IS SCRAPIE
Scrapie
A neurodegenerative disease that has been found in certain flocks of sheep for centuries
WHAT IS BSE
Mad Cow disease caused by feeding infected sheep carcasses to cattle
what is cjd
A Human form of BSE caused by eating BSE infected beef
name 4 diseases caused by prions in non humans
Scrapie: sheep
TME (transmissible mink encephalopathy): mink
CWD (chronic wasting disease): muledeer, elk
BSE (bovine spongiform encephalopathy): cows
Humans are also susceptible to several prion diseases such as?
CJD: Creutzfeld-Jacob Disease
GSS: Gerstmann-Straussler-Scheinker syndrome
FFI: Fatal familial Insomnia
Kuru
Alpers Syndrome
when are prions usually diagnosed

what are prions resistant to


there is a failure to identify a scrapie specific.....
Usually only diagnosed fully on death of the individual affected


u.ve radiation

Failure to identify a scrapie specific nucleic acid either in prion preparations or infected brains using a variety of sophisticated techniques.
prions are also show resistance of


what isn't necessary for infectivity

what are prions susceptible to
Resistance of infectivity to agents which modify or damage nucleic acids


Nucleic acid is not necessary for infectivity

Infectivity is susceptible to reagents which destroy proteins
what are prions defined as
Prions are defined as "small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids
what are prions often called and why
Prion diseases are often called spongiform encephalopathies because of the post mortem appearance of the brain with large vacuoles in the cortex and cerebellum.