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18 Cards in this Set

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Radiation Therapists may administer drugs specific to
RT contrast , anesthetics, or IV fluids
the science of drugs including chemistry, sources, and actions of drugs
Pharmacology
established to govern the labeling, availability and dispensation of drugs in US
the Federal Food Drug and Cosmetic Act of 1938
the way drugs affect the body, attaches itself to a target site in the body called receptor site; combined effect alters the behavior of the targeted cell or enzyme
Pharmacodynamics
way drugs travel through the body to receptor site. Drug is absorbed, distributed and excreted, varies with individual patients
Pharmacokinetics
must be absorbed into the bloodstream, dosage, speed of absorption, route of entry, ph of recipient environment, solubility of the drug interaction with body chemistry
Absorption
drug travels circulatory system, bind with other proteins, cross specific membranes, to produce response~blood brain barrier, placenta
Distribution
liver detoxifies most all foreign substances entering body, changing into water soluble compounds to be excreted by kidneys; other organs, gallbladder, lungs, intestines also able to excrete; synergistic effect or accumulation can cause organ damage
Metabolism
detoxifies most all foreign substances entering body
liver
drugs leave body thru kidneys; lungs excrete substances that turn to gas; depends on body’s system, medication, radioactive drugs that have half life
Excretion
-immunologic reaction to a drug when patient has all ready been sensitized; drug acts as antigen and body developes antigens to drug
Allergic reaction
A severe, sometimes fatal allergic reaction characterized by a sharp drop in blood pressure, urticaria, and breathing difficulties that is caused by exposure to a foreign substance, such as a drug or bee venom, after preliminary or sensitizing exposure
anaphylactic shock
drug that commonly causes anaphylactic shock
Penicillin
body adapts to drug and greater doses are required to achieve effect
Tolerance
effect develops if the body is unable to detoxify; drug accumulates in tissue and becomes toxic
Cumulative effect
is the Cumulative effect ever desired
yes
Cumulative effect can cause
depression
An unusual individual reaction to food or a drug
Idiosyncratic