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18 Cards in this Set
- Front
- Back
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Radiation Therapists may administer drugs specific to
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RT contrast , anesthetics, or IV fluids
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the science of drugs including chemistry, sources, and actions of drugs
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Pharmacology
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established to govern the labeling, availability and dispensation of drugs in US
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the Federal Food Drug and Cosmetic Act of 1938
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the way drugs affect the body, attaches itself to a target site in the body called receptor site; combined effect alters the behavior of the targeted cell or enzyme
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Pharmacodynamics
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way drugs travel through the body to receptor site. Drug is absorbed, distributed and excreted, varies with individual patients
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Pharmacokinetics
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must be absorbed into the bloodstream, dosage, speed of absorption, route of entry, ph of recipient environment, solubility of the drug interaction with body chemistry
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Absorption
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drug travels circulatory system, bind with other proteins, cross specific membranes, to produce response~blood brain barrier, placenta
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Distribution
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liver detoxifies most all foreign substances entering body, changing into water soluble compounds to be excreted by kidneys; other organs, gallbladder, lungs, intestines also able to excrete; synergistic effect or accumulation can cause organ damage
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Metabolism
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detoxifies most all foreign substances entering body
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liver
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drugs leave body thru kidneys; lungs excrete substances that turn to gas; depends on body’s system, medication, radioactive drugs that have half life
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Excretion
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-immunologic reaction to a drug when patient has all ready been sensitized; drug acts as antigen and body developes antigens to drug
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Allergic reaction
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A severe, sometimes fatal allergic reaction characterized by a sharp drop in blood pressure, urticaria, and breathing difficulties that is caused by exposure to a foreign substance, such as a drug or bee venom, after preliminary or sensitizing exposure
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anaphylactic shock
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drug that commonly causes anaphylactic shock
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Penicillin
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body adapts to drug and greater doses are required to achieve effect
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Tolerance
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effect develops if the body is unable to detoxify; drug accumulates in tissue and becomes toxic
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Cumulative effect
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is the Cumulative effect ever desired
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yes
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Cumulative effect can cause
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depression
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An unusual individual reaction to food or a drug
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Idiosyncratic
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