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23 Cards in this Set
- Front
- Back
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What happens to gastric pH in the elderly?
What happens to renal filtration fraction? |
Increases
Increases |
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Clearance of a medication is a function of what two paramaters?
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Volume of distribution and half life
so anything that alters these alters drug clearance |
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True or false: there is generally a decline in phase I metabolism?
Is there a reduction in cytochrome activity? |
True
Nope! |
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True or false: there is generally a decline in phase II metabolism
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false
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In the elderly, changes in dosing are usually associated with (RENAL/HEPATIC) metabolism?
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renal
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What are some long acting benzos you probably want to avoid?
what about SSRI? |
diazepam, flurazepam, chlordiazepoxide
fluoxetine |
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First line treatment for hypertension in the elderly?
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diuretics
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Preferred therapy for hyperlipidemia in the elderly?
what do you need to get a baseline for? |
statins
creatnine |
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Preferred treatment for MI in the elderly?
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thrombolytics are a class IIa recommendation in pts >75 presenting w/in 12 hours
some limited data suggests angioplasty may be preferred |
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What is the most common reason for hospitalization in the elderly?
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heart failure
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What is/are the treatment for heart failure in the elderly?
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ACEs and B-blockers unless contraindicated
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Treatment of choice for AFib with:
1. No risk factors 2. One moderate risk factor 3. any high risk or >1 moderate |
1. ASA 81-325 mg qd
2. ASA 81-325 mg OR warfarin 3. Warfarin |
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First line antiplatelet therapy for stroke in the elderly?
alternative? |
ASA
clopidogrel = alternative |
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First line treatment for osteoarthritis in the elderly?
for more severe? |
APAP
NSAIDs |
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Treatment for Rheumatoid Arthritis?
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DMARDS, NSAIDs, low dose corticosteroids
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Why should you try to avoid hypoglycemia?
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risk of falls and fractures
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True or false
sulfonylureas have a high risk of hypoglycemia? |
true
initial dose should be low and titrate slow |
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True or false
metformin has a high risk of hypoglycemia? what does metformin have an increased risk of? |
false
lactic acidosis (relative contraindication in pts >80) |
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True or false
thiazolidinediones have a high risk of hypoglycemia? what else can they cause? |
false
fluid retention |
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True or false
Insulin poses a high risk for hypoglycemia |
true
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Usual caloric range for elderly is?
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1900-2400 cal/day depending on activity
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BMI range for the elderly?
Is albumin a specific or non-specific indicator of nutritional status? An albumin level of <___ is associated w poor nutrition? |
22-27
non-specific <3.5 g/ml |
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a sharp decline in ______ may indicate poor nutrition?
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cholesterol
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