Intramebranous Ossification

Front 1

Name the first step of Intramembranous ossifcation.

Back 1

1. Ossification centers form withing thickened areas of mesenchyme
-cells in thickened mesenchyme divide to and differentiate into osteoprogenitor cells
-the opt become osteoblasts that secrete osteoid forming multiple ossifcation centers

Front 2

Name the second step of intramembranous ossifcation

Back 2

2. Osteoid undergoes calcification
-calcification occurs as calcium salts are deposited onto the osteoid and crystallize.
-Calcification entraps osteoblast w/in lacunae in matric forming osteocytes.

Front 3

Name the third step of intramembranous ossifcation

Back 3

Woven bone and its surrounding periosteum form

Front 4

Name the fourth step of intramembranous ossification

Back 4

Lamellar bone replaces woven bone, as compast and spongy bone form.

Front 5

Name the first step in Endochondral Ossification.

Back 5

The fetal hyaline cartilage model develops.
-hyaline cartilage forms along with chondrocytes, surrounded by a perichondrium

Front 6

Name the second step of endochondral ossification

Back 6

Cartilage calcifies, and a periosteal bone collar forms.
-chondrocytes die as cartilage calcifies forming large holes
-stem cells in perichondrium form osteoblasts
-perichondrium becomes periosteum
-osteoblasts w/in internal layer of periosteum secret osteoid around cartilage shaft producing periosteal bone collar

Front 7

Name the third step of endochondral ossification.

Back 7

Primary Ossification center forms in the diaphysis.
-osteoblasts replace calcified cartilage with bone tissue

Front 8

Name the fourth step in Endochondral Ossification

Back 8

Secondary Ossification center forms in the epiphyses
-hyaline cartilage in the center of each epiphysis calcifies and begins to regenerate.

Front 9

Name the fifth step in Endochondral Ossification.

Back 9

Bone replaces cartilage, escept the articular cartilage and epiphyseal plates.

Front 10

Names the sixth and final step of endochondral ossification.

Back 10

Epiphyseal plates ossify and form epiphyseal lines
-this happens between the ages of 10-25.