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8 Cards in this Set

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9 reactions that occur in the cytoplasm:
1. Glycolysis
2. Gluconeogenesis (most)
3. HMP
4. Glycogenesis/olysis
5. FA Synthesis
6. NT synth/breakdown
7. TAG synthesis
8. Cholesterol biosynthesis
9. Urea cycle (part)
What 2 pathways take place in 2 compartments and where?
1. Gluconeogenesis
2. Urea cycle

-Part in cytosol
-Part in mitochondrial matrix
4 reactions that completely take place in mito matrix:
1. TCA cycle
2. FA oxidation/ketogenesis
3. Amino acid oxidation
4. ETC/oxidative phosphorylation
What 2 enzymes are specific to lysosomes?
-Acid phosphatase
-Acid hydrolyase
What is a metabolon?
A physical association of enzymes for catalyzing sequential steps; sometimes but rarely on the same enzyme even.
What is substrate channeling?
The grouping of metabolic intermediates for sequential steps -> results in a metabolon.
What is futile cycling?
The simultaneous degradation and synthesis of a metabolic intermediate.
How is futile cycling avoided?
By compartmental segregation which sequesters intermediates from cell compartments.