• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/23

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

23 Cards in this Set

  • Front
  • Back
Restrictive Lung Diseases Pathophysiology
Inflammatory damage leads to frosis of alveolar walls wiping out groups of alveoli.
Restrictive Lung Diseases Clinical Findings
Decreased pulmonary compliance
Mismatched ventilation and perfusion
Mechanical barrier to oxygen diffusion
Increased pulmonary blood pressure leading to cor pulmonale and death
May see "honeycomb" lung on autopsy or radiography
Hear dry "velcro crackles"
Where is most fibrosis of the lung seen?
The lower lobes, where there is less air and more vasculature (exception asbestosis)
Pulmonary fibrosis secondary to autoimmune disease
Rheumatoid Lung
Scleroderma Lung
Sjogren's Lung
Pulmonary fibrosis due to pneumoconiosis
Asbestosis
Berylliosis
Hard metal
may all cause farmer's lung
Desquamative Interstitial Pneumonitis (DIP)
Fibrosis of lung
Alveoli clog with lipid and mucin laden macrophages
May turn into Hamman-Rich
Treat with Steroids
Nonspecific interstitial pneumonitis
All septa involved about equally
No "honeycomb" cysts
Treat with glucocorticoids
Paraquat ingestion
severe rapid fibrosis of the lungs
Polymyositis-Dermatomyositis
antibodies against t-RNA (anti-Jo)
Idiopathic pulmonary hemorrhage
babies
can be fatal
Angiosarcoma
diffuse pulmonary hemorrhage
Wegener's
Pulmonary capillaritis
Other Fibrosing Lung Conditions
Histiocytosis X (coffee bean nuclei)
GVH disease lung (chemo)
ARDS
Bronchopulmonary Dysplasia
Diffuse Pulmonary Amyloidosis
Lymphangioleiomyomatosis
Rare
Proliferation of smooth muscle throughout lung
Women in childbearing years
Treat with hormones
Alveolar proteinosis
Alveoli filled with surfactant and proteinacious goop
Rare fibrosis
Congenital form with surfactant protein B absent
Hamman-Rich Syndrome
Pulmonary fibrosis
Middle-aged to older people
Contraction of some tissue causes dilation of some spaces "honeycomb" cysts
Obvious chronic inflammation
No pathogen
Patients have abnormal T-cells
Untreatable
Sarcoidosis
Multi-system disorder
Non-caseating granulomas
Young adults
Hypercalcemia
Erythema nodosum
Sarcoidosis in AV node (rare)
Granulomas are sharply circumscribed
Asteroid bodies may be present in giant cells
Kveim test - outdated
Steroid treatment
Good Pasture Disease
Antibodies against basement membranes of lung and kidneys
Eosinophilic Pneumonias
Many causes
Usually have pulmonary infiltrates and increased eosinophils in the blood
Aspergillus, microfilaria worms, some drugs
Lipid Pneumonia
Exogenous - lungs response to aspirated oil, more unsaturated leads to worse inflammation
Endogenous - build up of surfactant
Bronchocentric granulomatosis
Aspergillus
Caseating granulomas
Pulmonary fibrosis often causes what acid/base disorder?
Respiratory alkalosis
Bronchiolitis Obliterans Organizing Pneumonia (BOOP)
Loose CT develops and plugs the respiratory bronchioles