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26 Cards in this Set
- Front
- Back
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Thyroid hormones and quinolones malabsorption |
cations - Ca, Mg, Fe, antacids (PPI, H2), sucralfate, and cholestyramine need to separate by 12 hours |
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Drugs that decrease CYP450 (metabolism) (can increase INR in coumadin pts) |
SICK FACES . COM Group Sodium valproate Isoniazid Cimetidine Ketoconazole Fluconazole Alcohol..binge drinking Chloramphenicol Erythromycin Sulfonamides Ciprofloxacin Omeprazole M etronidazole Grapefruit juice |
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CYP450 3A4 induces |
CRAP GPS Carbemazepines Rifampin Alcohol (chronic) Griseofulvin PHenobarbitone Sulphonylureas |
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Drugs that increase Risk of Statin Toxicity |
fibrates (gemfibrozil 15x> fenofibrate) Azoles amiodorarone Erythro/Clarithro Protease inhibitors Verapamil/diltiazem (fewest drug interactions with pravastatin) |
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when not to use bactrim |
pt on warfarin pt on MTX allergy elderdly pt with renal insufficiency can cause hyperkalemia in CKD pts, ACEs |
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hyperkalemia meds |
ACEis, arbs, K sparing diuretics, bactrim, nsaids, salt substitutes |
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drug induced edema |
dihydropyridines pioglitazone NSAIDS estrogen and testosterone pramipexole gabapentin and pregabalin omeprazole |
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drugs that increase Uric Acid |
diuretics niacin cyclospirine topiramate (also acts as carbonic anhydrase inhibitor causing NAGMA) ethambutol/pyrazinamide |
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SSRI effects |
increases risk of GI bleeding hyponatremia (especially in elderly, female, concomitant diuretics, low body weight) |
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hyponatremia |
SSRIs HCTZ (30%) carbamazepine |
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who should receive drug therapy in osteporosis |
- postmenopausal w/ T score < -2.5 in absence of risk factors - postmenopausal women with T score < 2.0 in presence of risk factor/s -hx of fracture after 40 -family hix of hip fracture in 1st degree -smoker -body weight< 127 lbs |
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when to start tx for osteoperosis |
-2.5 or less -1-2.4 with fractrue hx of vertebral or hip fx high risk FRAX hip fx score > 3% or FRAX major fracture score > 20% |
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Osteoperosis contrindications |
bisphosphonate - severe GERD, renal failure SERMS - VTE and stroke, hot flashes worse teriparatide - kidney stones, gout denosumab - skin conditions |
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medications and fall risk |
TCAs benzodiazepines vasodilators antipsychotics |
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hyperthyroid in elderly |
apathetic hyperthyroidism -anorexia -weight loss -constipation -less tachycardia -absence of typical symptoms |
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delerium causes |
infection medications bladder catheter restraints decreased sleep new surroundings ETOH withdrawal meds TCAs, antipsychotics, antihistamines, antiemetics, antiparkinsonian, analgesics, steroids, quinolones, sedatives |
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Incontinence |
urge - oxybutnin, imipramine, bladder training stress - Kegels, alpha adrenergic agonists overflow - remove offending meds, alpha blockers for BPH |
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BPH tx |
1st line is alpha blockers - tera/doxa/tamuloosin 2nd line - finasteride (takes months to work) 3rd line TURP |
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Serotonin syndrome |
SSRIs, tramadol, linezolid, meperidine, dextromethorphan, TCA, MAOI, buspirone, trazodone |
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neuroleptic malignant syndrome etiology |
Discontinuation of parkinsons meds haldol chlorpromazine clozapine |
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ASC-US |
woman age 21-24: repeat cytology in one year woman age > 25: HPV DNA testing |
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Rhinitis medicamentosa |
occurs in pts with chronic use of vasoconstrictor nasal sprays get worsening nasal congestion tx. intranasal steroids |
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TCA OD |
resp. depression, hypotension, tachycardia, seizures, coma, wide complex tach with QRS > 100 ms |
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presbycusis |
progressive, b/l, high frequency hearing loss |
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randomization |
ensure that the groups being studied differ from one another only in terms of the intervention controls for known and unknown variables |
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allergic rhinitis tx |
intranasal steroids |
