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3 Cards in this Set
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Intermediate filament involved in |
Mechanical scaffold for the cell and tissue * No role in movement |
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Structure |
Monomer, dimer, tetramer, protofilament, intermediate filament Usually 8 protofilaments -> 1 intermediate filament N-terminal head, rod-like alfa-helical domain, C-terminal tail |
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Intermediate filament proteins |
*Tissue specific Keratin - cytokeratin in epithelial cell (soft) keratin in hair, nails etc. (hard) Vimentin - connective tissue, smooth muscle, leukocytes Desmin - muscle cells Peripherin - peripheral neurons Neurofilaments - neurons of CNS Alfa-internexin, nestin - neuronal precursors cells Lamins - nuclear lamins (ubiquitous protein |
