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39 Cards in this Set

  • Front
  • Back
-skin+ accesory organs
-hair, nails, and cutaneous glands
Integumentary System
3 layers of the skin
1. Dermis
2. Epidermis
3. Hypodermis
-protection
-water barrier
-vitamin D synthesis
-sensation
-thermoregulation
Functions of Integumentary system
-keritanized stratified squamous epithelium
-most superficial layer
-avasculature layer so depends on diffusion of nutrients from CT underlayer
-fully replaced about every 4 weeks
-4 to 5 layers
Epidermis
-keratinocytes
-melanocytes
-dendritic cells
-tactile cells
-also stem cells
cells in Epidermis layer
1)-Protein that makes up nail and thick skin
-nearly all visible epidermal cells are this

2)-main pigement for skin and protects from sun damage
-occure only in stratum basale
1) keratinocytes

2) melanocytes
1) -macrophages (eat up bacteria/prevent infection)
-immune cells
-found in straum spinosum and stratum granulosum

2)-touch receptor
-found in basal layer of epidermis
1) dendtiric cells

2) tacticle cells
-single layer of cuboial cells
-primary purpose: mitosis and create new skin cells
-contains stem cells for constant mitosis, malanocytes, tactile cells, and keratinocytes (mostly)
Stratum Basale
-cells have spine-like projections
-cells flatten as they move up
-keratinocytes and dentritic cells
-can have up to 10 layers of cells so in most skin is the thickest
Stratum Spinosum
-consists of 3-5 layers of flat keratinocytes so more in thick skin than thin
-keratinocytes contain dark granules
-dendritic cells
Stratum Granulosum
-only present in thick skin (palms/soles, finger tips)
-only there is all 5 layers are present
-keratinocytes
-cells have no nuclei or other organelles
-pale/featureless
Stratum Lucidum
-up to 30 layers of dead, scaly keratinized cells
-no nucleus
-shed constantly
-thickest epidermal layers of the skin
-layer that provides resistance to abrasion, penetration, and water loss
Stratum Corneum
-produced deep in epidermis by mitosis of stem cells in the stratum basale
-moved upward by dividing cells below, begins between s. spinosum and s. granulosum
-creates the water barrier
-dust mites
Keritinization
layers of skin from superficial to deep
Corneum-> lucidum -> Granulosum -> Spinosum -> Basale
-consists of CT (mostly collagen), blood vessels, muscle, glands, hair, and nails
-hair follicles and nail roots are embedded here
-skeletal muscles that produce a smile, wrinkle of forhead, or eyebrow lift attach to here
-2 layers
Dermis
2 layers of the dermis
1. Papillary

2. Reticular
-part of Dermis
-thin, aerolar CT
-allows passage of vessels, WBC's
-especially rich in small blood vessels
Papillary Layer of Dermis
-part of Dermis
-thick, dense irregular CT
Reticular Layer
-Connects skin to the rest of tissues (not really part of skin)
-subcutaneous fat, aerolar CT, vessels, nerves, and adipose tissue
-aerolar or adipose tissue between skin and muscle
Hypdermis
-binds skin to other tissues
-cushions
-energy storage
-insulation
function of hypodermis
3 factors for skin color
1. melanin
2. hemoglobin
3. carotene
-brown/black pigment
-produced by melanocytes
-taken up by keratinocytes
-absorbs UV radiation
Melanin
1. red/pink from blood

2. yellow color of stratum corenum
1. hemoglobin

2. carotene
3 types of glands in accesory organs
1. Sudoriferous

2. Sebaceous

3. Ceruminous
-sweat glands
- 2 types
Sudoriferous
2 types of Sudeoriferous glands
1. Merocrine

2. Apocrine
-watery perspiration
-widely distributed over the body but especially on palms, soles, and forehead
-respond to heat
-throughout the body; active at birth
Merocrine Sweat Glands
-thicker, milkier perspiration
-occur in groin, anal region, axilla, and aerola; also in mature males beard area
-contains fatty acids (eaten by bacteria)--BO
-responds to stress, sex steroids
apocrine sweat glands
-Oil Glands
-Ducts open to hair follicle
-lubricates and waterproofs hair
-upside down heart shaped structure
-sebecum/oil
Sebaceous
-only found in audiory canal
-waterproofs/protects ear canal from dirt/debris and tempanic membrane pliable
-cerumen (earwax)
Ceruminous
-consists of hard keratin
-composed of bulb, root, and shaft
-protects the nose, eyelids, ear
-insulation of head
Hair
1. hair of fetus (only present before birth)

2. Fine/pale hair ("fleece")
-2/3 of females and 1/10 of males, most children
1. Lanugo

2. Vellus
-longer/coarser
-pigmented (after puberty)
-legs, pubic hair, scalp, male face
-differences in apparent hairiness due to texture/pigment
Terminal hair
1. eumelanin

2. pheomelanin
1. brown/black

2. red/yellow
1. -involves only the epidermis and part of dermis
-marked by redness, slight edema, and pain

2. -involves the epidermis and part of teh dermis
-may be red, tan, or white and is blistered and very painful
-2 weeks to several months to heal
1. First degree burn

2. second degree burn
-full thickness burn
-all of the dermis and often some deeper tissues (muscle, bone) are destroyed
-no dermis remains so skin can regenerate only from edges of the wound or skin graft for repair
-primary danger is dehydration and infection
Third degree burn
-basale, rarely metastisizes
-easiest type to treat
Basal cell carcinoma
-spinosum
-can metastisize into lymphoma
Squamous cell carcinoma
-melanocytes, from preexisting mole
-rare but lethal
-usual ftal if metastisizes
Malignant Melanoma