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106 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Bacitracin Zinc (AK-Tracin) is a ____
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antiseptic
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Bacitracin Zinc + Polymyxin B Sulfate (10,000)
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Polysporin
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Antiseptic
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Bacitracin Zinc + Polymixin B Sulfate + Neomycin Sulfate
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Neosporin
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Antiseptic
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Bactine
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Benzalkonium Chloride w/ lidocaine
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antiseptic
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Lanacane
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benzocaine 20% and benzethonium chloride (0.1%)
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antispetic
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Telfa are ___ pads
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nonstick
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Hydrophilic polymer + potassium salt
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Urgent QR
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wound must be clean 1st
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2-Octyl Cyanoacrylate (containing paraben)
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Liquid Band-Aid
(same stuff in super glue, derma-bond) |
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8-Hydroxyquinoline
Alcohol Oil of Cloves |
New Skin
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Liquid adhesive
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Camphor 3%
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counterirritant
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Camphor <1%
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local anesthetic
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Phenol 2.5%
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local anesthetic
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Tannic acid
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skin protectent
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4 factors causing acne
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Follicular hyperkeratinization
Increase sebum production Inflammation Propionibacterium acnes |
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Retinoid that reduces hyperkertinization, decreases adhesion of cells, increases shedding, and prevents blockage.
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Tretinoin
(all-trans-retionic acid) |
Retin-A
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Retinoid used systemically, treats the 4 factors, teratogenic, and causes hypervitaminosis A.
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Isotretinoin
(13-cis-retinoic acid) |
Accutane
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Retinoid for psoriasis, not used for acne, hypervitaminosis A, can remain in a person's system a long time (up to a year).
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Acitretin
(2nd gen) |
Soriatane
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Retinoid that's comedolytic, keratolytic and AI; prodrug; shows selective activity for RAR-beta and RAR-gamma.
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Tazarotene
(Tazorac) |
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Retinoid that's comedolytic, keratolytic and AI; binds with RARs (not RXR's or CRABPs); apart of Epiduo
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Adapalene
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Differin
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T-Cell modulators are used for ____
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psoriasis
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T-mod that fuses proteins: LFA-3 and human IgG and inhibits cutaneous T-cell activation and proliferation
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Alefacept
(Amevive) |
IM injections
AE: pharyngitis, flu like symptoms, chills, N/V, HA, dizziness |
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TNF-alpha blockers for psoriasis
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Etanercept (Enbrel)
Infliximab (Remicade) Adalimumab (Humira) |
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TNF-alpha that's IV
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Infliximab (Remicade)
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T-mod that prevents IL-2 and IL-23 binding to receptors; SC admin; only drug in class.
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Ustekinumab (Stelara)
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AE:
URI HA Nasopharyngitis Arthalgia |
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Psoriasis where lesions are mostly in folds of skin
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inverse
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Psoriasis where is typically triggered by bacterial infection
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Guttate
(<2% of pts) |
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Psoriasis where is usually localized in palms and soles (rarely generalized)
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pustular
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Psoriasis that's widespread and emergency situation
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erythrodermic
(looks like pt has been burned) |
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Non-pharm treatment for psorasis
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Stress-reduction
Moisturizers Oatmeal baths Skin protectants Use sunscreen SPF 30 or greater Eliminate skin irritants Climatotherapy --> bathing in very salty water and using sun rays to help (Dead Sea) Emollients |
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Aloe vera, petrolatum, baby oil, mineral oil are examples of ____
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emollients
(good non-pharm to trt psoriasis along with corticosteroids) |
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When to phototherapy in psoriasis trt
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when moderate to severe
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Coal tar can be combined with UV light in severe psoriasis?
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yes
(called Goeckerman regimen) |
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Can salicylic acid be used in kids? which light can it not be used with?
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no
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UVB
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Which topical agent for psoriasis has limited efficacy when used alone?
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salicylic acid
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Recommended to use less than ___ grams of top corticosteroids per week
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50
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Which topical agent for psoriasis inhibits T-cell lymphocyte activity & inhibs keratinocyte proliferation?
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Vitamin D3 analog
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Taclonex?
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Calcipotriene + Betamethasone ointment
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(UVA light inactivates)
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Tazorac is approved in kids ___ years and older
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12
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Dritho-Creme, Dritho-Scalp, Zithranol-RR are what class of drugs
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anthralin
(psoriasis) |
MOA: not fully understood; thought to effect mitochondria
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Ingram regimen
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Anthralin
tar bath UV light (inpatients) |
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Which topical agent for psoriasis is effective for refractory plaques?
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anthralin
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Which 2 topical agents for psoriasis cause staining of skin?
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coal tar
anthralin |
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Which topical agent for psoriasis doesn't work for plaque psoriasis?
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topical calcineurin inhibitors
(BBW for malignancy) |
Used off-label for facial and intertriginous psoriasis
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Which type of UVB is used in Goeckerman and Ingram regimens for enhanced efficacy
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Broadband
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What helps with UVA SE's?
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milk
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Systemic alternative meds for psoriasis?
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Azathioprine
Hydroxyurea Leflunomide Mycophenolate Sulfasalazine Tacrolimus 6-thioguanine |
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Mild-moderate psoriasis trt order?
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topical --> topical + phototherapy --> topical + systemic
(all with moisture controlling agents) |
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Moderate-severe psoriasis trt order?
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system +/- topical or phototherpay --> more potent systemic (or 2+ systemic agents) +/- top --> BRM +/- others
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Which psoriasis is good for emollient trt?
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inverse
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Which 3 psorasis is good with MTX?
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inverse
pustualr erythrodermic |
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Which psoriasis is good with BMR's?
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pustular
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Which 3 psoriasis is good with phototherapy?
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plaque
pustular guttate |
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Which psoriasis is good with inflizimab?
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erythrodermic
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When not to self treat psoriasis?
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if >10% BSA
in recalcitrant cases if <2 yo |
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Cormobidities of psoriasis?
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Psoriatic arthritis (PsA)
Metabolic syndrome Crohn’s disease Ulcerative colitis Multiple sclerosis Psychological Illness |
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Where do loops cause otoxicity?
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srtria vascularis (which secretes endolymph into the scala media --> this is where the spiral organ of corti is located)
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What are the inner hair cells (RM 1 row) responsible for in the spiral organ of corti?
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hearing
(apart of CN8; drugs target here 1st) |
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What are the outer hair cells (RM 3 rows) responsible for in the spiral organ of corti?
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regulating tension of the basilar membrane, and tuning of inner hair cells
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Where do AG's, cisplatin, and salicylates target to cause otoxicity?
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hair cells of the spiral organ of corti
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Which sound pitch do AG's and cisplantin affect first?
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high pitch
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Short fibers near the oval windown pick up ___ frequency.
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high
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Long fibers near the apex pick up ___ frequency.
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low
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What is chlorhexidine gluconat 4%?
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Hibiclens
(topical antiseptic) |
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What is povidone-iodine 10% solution used for?
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antiseptic
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Dermabond peels off in ___ days. How many layers do you apply?
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5-10
3 layers |
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What type of wounds are CI to use with dermabond? (4)
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jagged lacerations
bites punctures crush wounds |
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Is phenol 2.5% FDA category 1?
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no
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Which wounds are prone to get tetanus?
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older than 6 hours
jagged crushing, heat or cold wounds infected wounds contaminated wounds non-sterile injection wound |
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DOC for animal bites?
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Amoxicillin-clavulanate potassium 500/125 mg PO tid or 875/125 mg PO bid
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When to do PEP for rabies?
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From bats
High risk area |
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Doses of PEP rabies vaccine?
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days 0,3,7,14
in deltoid of arm |
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When does it become an irreversible damaging burn
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exceeds 113 degrees
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With this burn you get scarring and hyperpigmenation
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2nd degree
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With this burn grafting is a MUST!
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3rd degree
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What is the Lund Browder diagram good for?
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for kids in determining amount burned
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When to NOT self treat burn?
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Bigger than 3 inches
Multiple large burns High infection risk Burned on hands, feet, face, groin, buttocks or major joint |
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Which two broad creams are used for burns?
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Silver sulfadiazine
Mafenide acetate CI: if sulfa allergy |
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Do burns get 2ndary dressing?
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yes
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How long do you use cold water on a new burn?
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20 minutes
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Hydrocortisone on burns?
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no can be bad if open skin
ORAL nsaids |
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Which 3 local anestheics are FDA class 1?
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Benzocaine
Lidocaine Pramoxine |
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Why is Telfa good for burns?
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Bc need a non-stick dressing
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Petrolatum, Shark liver oil, A & D oint,
Cocoa butter, zinc oxide are all ____ |
skin protectents
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good to reduce pain and prevent drying, etc
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____ are very beneficial for sunburns
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NSAIDs
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Thermazene
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Silver sulfadiazine
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Three good things for marine injuires?
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Acetic acid (vinegar)
Baking soda Meat tenderizer |
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Three things not to do for snake bite?
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incise wound
suction or elevate above heart |
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Do you hold a seizuring pt down?
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no
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When suggested to use paste of nicotine?
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insect stings for pain relief
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Camphor/Menthol good for insect sting because stops the ____
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itching
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Name some drugs that increase heat related illnesses?
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Antispasmodics
Diuretics Beta-blockers Calcium channel blockers Anti-Parkinson medicines Synthroid at high dose Saliclylates Neuroleptics Phenothiazines Sedatives Antihistamines Anticholinergics MAOIs TCAs Alcohol and illegal drugs |
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Where should you place cool compresses on a person having a heat stroke?
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under arm pits
groin Should you elevate their feet? |
yes
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Gauze and toppers are ___ dressings?
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primary
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Tyrosinase is impt for producing ___
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melanin
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A person with Addison's disease or hyPOfunctiong adrenal cortex will look what color?
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bronze
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Name some drugs that increase heat related illnesses?
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Antispasmodics
Diuretics Beta-blockers Calcium channel blockers Anti-Parkinson medicines Synthroid at high dose Saliclylates Neuroleptics Phenothiazines Sedatives Antihistamines Anticholinergics MAOIs TCAs Alcohol and illegal drugs |
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Where should you place cool compresses on a person having a heat stroke?
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under arm pits
groin Should you elevate their feet? |
yes
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Gauze and toppers are ___ dressings?
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primary
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Tyrosinase is impt for producing ___
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melanin
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A person with Addison's disease or hyPOfunctiong adrenal cortex will look what color?
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bronze
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Languo?
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Delicate, unpigmented hair
5-6 month of fetal development replaced by either vellus or terminal hair |
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Vellus hair is located where?
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EVERYWHERE except on scalp, eyelids, and eyebrows --> that's terminal hair
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This is the muscle responsible for goosebumps
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arrector pili
(smooth muscle) |
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Hair follicle is apart of the dermis or epidermis?
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epidermis tho root is in dermis
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3 layers of hair? What's the bulk?
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Medulla (inner) --> cortex --> cuticle
cortex = bulk |
Medulla only part with soft keratin
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What are 3 non-retinoid keratoyltics used for psoraisis
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salicylic acid
benzoyl peroxide propylene glycol |
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