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106 Cards in this Set

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Bacitracin Zinc (AK-Tracin) is a ____
antiseptic
Bacitracin Zinc + Polymyxin B Sulfate (10,000)
Polysporin
Antiseptic
Bacitracin Zinc + Polymixin B Sulfate + Neomycin Sulfate
Neosporin
Antiseptic
Bactine
Benzalkonium Chloride w/ lidocaine
antiseptic
Lanacane
benzocaine 20% and benzethonium chloride (0.1%)
antispetic
Telfa are ___ pads
nonstick
Hydrophilic polymer + potassium salt
Urgent QR
wound must be clean 1st
2-Octyl Cyanoacrylate (containing paraben)
Liquid Band-Aid

(same stuff in super glue, derma-bond)
8-Hydroxyquinoline
Alcohol
Oil of Cloves
New Skin
Liquid adhesive
Camphor 3%
counterirritant
Camphor <1%
local anesthetic
Phenol 2.5%
local anesthetic
Tannic acid
skin protectent
4 factors causing acne
Follicular hyperkeratinization
Increase sebum production
Inflammation
Propionibacterium acnes
Retinoid that reduces hyperkertinization, decreases adhesion of cells, increases shedding, and prevents blockage.
Tretinoin
(all-trans-retionic acid)
Retin-A
Retinoid used systemically, treats the 4 factors, teratogenic, and causes hypervitaminosis A.
Isotretinoin
(13-cis-retinoic acid)
Accutane
Retinoid for psoriasis, not used for acne, hypervitaminosis A, can remain in a person's system a long time (up to a year).
Acitretin
(2nd gen)
Soriatane
Retinoid that's comedolytic, keratolytic and AI; prodrug; shows selective activity for RAR-beta and RAR-gamma.
Tazarotene
(Tazorac)
Retinoid that's comedolytic, keratolytic and AI; binds with RARs (not RXR's or CRABPs); apart of Epiduo
Adapalene
Differin
T-Cell modulators are used for ____
psoriasis
T-mod that fuses proteins: LFA-3 and human IgG and inhibits cutaneous T-cell activation and proliferation
Alefacept
(Amevive)
IM injections

AE: pharyngitis, flu like symptoms, chills, N/V, HA, dizziness
TNF-alpha blockers for psoriasis
Etanercept (Enbrel)
Infliximab (Remicade)
Adalimumab (Humira)
TNF-alpha that's IV
Infliximab (Remicade)
T-mod that prevents IL-2 and IL-23 binding to receptors; SC admin; only drug in class.
Ustekinumab (Stelara)
AE:
URI
HA
Nasopharyngitis
Arthalgia
Psoriasis where lesions are mostly in folds of skin
inverse
Psoriasis where is typically triggered by bacterial infection
Guttate
(<2% of pts)
Psoriasis where is usually localized in palms and soles (rarely generalized)
pustular
Psoriasis that's widespread and emergency situation
erythrodermic
(looks like pt has been burned)
Non-pharm treatment for psorasis
Stress-reduction
Moisturizers
Oatmeal baths
Skin protectants
Use sunscreen SPF 30 or greater
Eliminate skin irritants
Climatotherapy --> bathing in very salty water and using sun rays to help (Dead Sea)
Emollients
Aloe vera, petrolatum, baby oil, mineral oil are examples of ____
emollients
(good non-pharm to trt psoriasis along with corticosteroids)
When to phototherapy in psoriasis trt
when moderate to severe
Coal tar can be combined with UV light in severe psoriasis?
yes
(called Goeckerman regimen)
Can salicylic acid be used in kids? which light can it not be used with?
no
UVB
Which topical agent for psoriasis has limited efficacy when used alone?
salicylic acid
Recommended to use less than ___ grams of top corticosteroids per week
50
Which topical agent for psoriasis inhibits T-cell lymphocyte activity & inhibs keratinocyte proliferation?
Vitamin D3 analog
Taclonex?
Calcipotriene + Betamethasone ointment
(UVA light inactivates)
Tazorac is approved in kids ___ years and older
12
Dritho-Creme, Dritho-Scalp, Zithranol-RR are what class of drugs
anthralin
(psoriasis)
MOA: not fully understood; thought to effect mitochondria
Ingram regimen
Anthralin
tar bath
UV light

(inpatients)
Which topical agent for psoriasis is effective for refractory plaques?
anthralin
Which 2 topical agents for psoriasis cause staining of skin?
coal tar
anthralin
Which topical agent for psoriasis doesn't work for plaque psoriasis?
topical calcineurin inhibitors

(BBW for malignancy)
Used off-label for facial and intertriginous psoriasis
Which type of UVB is used in Goeckerman and Ingram regimens for enhanced efficacy
Broadband
What helps with UVA SE's?
milk
Systemic alternative meds for psoriasis?
Azathioprine
Hydroxyurea
Leflunomide
Mycophenolate
Sulfasalazine
Tacrolimus
6-thioguanine
Mild-moderate psoriasis trt order?
topical --> topical + phototherapy --> topical + systemic

(all with moisture controlling agents)
Moderate-severe psoriasis trt order?
system +/- topical or phototherpay --> more potent systemic (or 2+ systemic agents) +/- top --> BRM +/- others
Which psoriasis is good for emollient trt?
inverse
Which 3 psorasis is good with MTX?
inverse
pustualr
erythrodermic
Which psoriasis is good with BMR's?
pustular
Which 3 psoriasis is good with phototherapy?
plaque
pustular
guttate
Which psoriasis is good with inflizimab?
erythrodermic
When not to self treat psoriasis?
if >10% BSA
in recalcitrant cases
if <2 yo
Cormobidities of psoriasis?
Psoriatic arthritis (PsA)
Metabolic syndrome
Crohn’s disease
Ulcerative colitis
Multiple sclerosis
Psychological Illness
Where do loops cause otoxicity?
srtria vascularis (which secretes endolymph into the scala media --> this is where the spiral organ of corti is located)
What are the inner hair cells (RM 1 row) responsible for in the spiral organ of corti?
hearing
(apart of CN8; drugs target here 1st)
What are the outer hair cells (RM 3 rows) responsible for in the spiral organ of corti?
regulating tension of the basilar membrane, and tuning of inner hair cells
Where do AG's, cisplatin, and salicylates target to cause otoxicity?
hair cells of the spiral organ of corti
Which sound pitch do AG's and cisplantin affect first?
high pitch
Short fibers near the oval windown pick up ___ frequency.
high
Long fibers near the apex pick up ___ frequency.
low
What is chlorhexidine gluconat 4%?
Hibiclens
(topical antiseptic)
What is povidone-iodine 10% solution used for?
antiseptic
Dermabond peels off in ___ days. How many layers do you apply?
5-10
3 layers
What type of wounds are CI to use with dermabond? (4)
jagged lacerations
bites
punctures
crush wounds
Is phenol 2.5% FDA category 1?
no
Which wounds are prone to get tetanus?
older than 6 hours
jagged
crushing, heat or cold wounds
infected wounds
contaminated wounds
non-sterile injection wound

DOC for animal bites?
Amoxicillin-clavulanate potassium 500/125 mg PO tid or 875/125 mg PO bid
When to do PEP for rabies?
From bats
High risk area
Doses of PEP rabies vaccine?
days 0,3,7,14
in deltoid of arm
When does it become an irreversible damaging burn
exceeds 113 degrees
With this burn you get scarring and hyperpigmenation
2nd degree
With this burn grafting is a MUST!
3rd degree
What is the Lund Browder diagram good for?
for kids in determining amount burned
When to NOT self treat burn?
Bigger than 3 inches
Multiple large burns
High infection risk
Burned on hands, feet, face, groin, buttocks or major joint
Which two broad creams are used for burns?
Silver sulfadiazine
Mafenide acetate

CI: if sulfa allergy
Do burns get 2ndary dressing?
yes
How long do you use cold water on a new burn?
20 minutes
Hydrocortisone on burns?
no can be bad if open skin
ORAL nsaids
Which 3 local anestheics are FDA class 1?
Benzocaine
Lidocaine
Pramoxine
Why is Telfa good for burns?
Bc need a non-stick dressing
Petrolatum, Shark liver oil, A & D oint,
Cocoa butter, zinc oxide are all ____
skin protectents
good to reduce pain and prevent drying, etc
____ are very beneficial for sunburns
NSAIDs
Thermazene
Silver sulfadiazine
Three good things for marine injuires?
Acetic acid (vinegar)
Baking soda
Meat tenderizer
Three things not to do for snake bite?
incise wound
suction
or elevate above heart
Do you hold a seizuring pt down?
no
When suggested to use paste of nicotine?
insect stings for pain relief
Camphor/Menthol good for insect sting because stops the ____
itching
Name some drugs that increase heat related illnesses?
Antispasmodics
Diuretics
Beta-blockers
Calcium channel blockers
Anti-Parkinson medicines
Synthroid at high dose
Saliclylates
Neuroleptics
Phenothiazines
Sedatives
Antihistamines
Anticholinergics
MAOIs
TCAs
Alcohol and illegal drugs
Where should you place cool compresses on a person having a heat stroke?
under arm pits
groin

Should you elevate their feet?
yes
Gauze and toppers are ___ dressings?
primary
Tyrosinase is impt for producing ___
melanin
A person with Addison's disease or hyPOfunctiong adrenal cortex will look what color?
bronze
Name some drugs that increase heat related illnesses?
Antispasmodics
Diuretics
Beta-blockers
Calcium channel blockers
Anti-Parkinson medicines
Synthroid at high dose
Saliclylates
Neuroleptics
Phenothiazines
Sedatives
Antihistamines
Anticholinergics
MAOIs
TCAs
Alcohol and illegal drugs
Where should you place cool compresses on a person having a heat stroke?
under arm pits
groin

Should you elevate their feet?
yes
Gauze and toppers are ___ dressings?
primary
Tyrosinase is impt for producing ___
melanin
A person with Addison's disease or hyPOfunctiong adrenal cortex will look what color?
bronze
Languo?
Delicate, unpigmented hair
5-6 month of fetal development

replaced by either vellus or terminal hair
Vellus hair is located where?
EVERYWHERE except on scalp, eyelids, and eyebrows --> that's terminal hair
This is the muscle responsible for goosebumps
arrector pili
(smooth muscle)
Hair follicle is apart of the dermis or epidermis?
epidermis tho root is in dermis
3 layers of hair? What's the bulk?
Medulla (inner) --> cortex --> cuticle

cortex = bulk
Medulla only part with soft keratin
What are 3 non-retinoid keratoyltics used for psoraisis
salicylic acid
benzoyl peroxide
propylene glycol