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32 Cards in this Set

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Which of the following is not true regarding type I diabetes? (multiple choice)
1.Insulin levels are elevated in spite of hyperglycemia
2.The liver is actively synthesizing glucose to put into the circulation
3. Insulin production in the pancreas is compromised
4. If untreated the kidney secretes glucose in the urine
5. All of the above
6. 1 and 2
7. 1, 2 and 4
1 and 2
Which of the following is true regarding type II diabetes (multiple choice)
1. It usually presents itself in adults
2. Insulin production in the pancreas is compromised
3. Tissues are hypersensitive to insulin action
4. It is associated with low caloric intake
1. It usually presents itself in adults
Type II diabetes can be reversed in many patients by weight loss and exercise (multiple choice)
1. True
2. false
1. True
The initial source of energy used in an 100 Meter dash is: (multiple choice)
Glucose
ATP
Creatine phosphate
Glycogen
Fatty acids
Creatine phosphate
What is the energy source with the slowest rate of mobilization during exercise? (multiple choice)
Glucose
ATP
Creatine phosphate
Glycogen
Fatty acids
Fatty acids
When does a runner begin to feel the maximum amount of pain that is caused by metabolism? (multiple choice)
As fatty acids begin to be used
When glycogen stores are completely depleted
When ketone bodies begin to accumulate in the circulation
When pyruvate is being converted to lactate
All of the above
2, 3 and 4
2, 3 and 4
Which vitamins are affected by chronic alcoholism? (multiple choice)
Thiamine
Vitamin C
Vitamin A
All of the above
All of the above
What happens to the insulin/glucagon ratio during a drinking binge when blood alcohol gets elevated? (multiple choice)
It increases significantly
It decreases significantly
No change due to the alcohol
It increases significantly
What would you predict is the limiting factor in the survival time of a person who is starving?
c. the total triglyceride content in the body
Which of the following is occuring in a resting individual in the fed state?
c. muscle fatty acyl CoA synthetase is active
Under euglycemic conditions (normal blood glucose levels) the liver absorbs the majority of the glucose. When insulin is released during hyperglycemia, the tissue which takes up the majority of the glucose is:
a. muscle
Within an hour of ingesting a meal
c. muscle glycogen phosphorylase is dephosphorylated
Insulin stimulates glucose uptake in
c. Muscle, liver and adipose
In prolonged starvation which of the following will not be observed?
e. a and d
Within an hour of ingesting a meal a variety of signals affect cellular metabolism. Which of the following will NOT be happening?
b. acetoacetate production in the liver
The first muscle energy source to be consumed during a 100 meter dash is:
c. creatine phosphate
Proteins that contribute to energy utilization include
e. all of the above
Alcohol metabolism leads to
f. 1, 3 and 4
The concentration of leptin in the circulation is a function of
b. the amount of body fat
Which of the following energy sources is likely to be the limiting factor that leads to the "wall" that marathon runners reach late in the race?
c. monosaccharides
The following statement is found in wikipedia regarding the microsomal ethanol oxidizing system. "The MEOS pathway requires oxidation of NADH to NAD, which consumes ATP and dissipates heat, thus leading to the hypothesis that long term drinkers see an increase in resting energy expenditure." Why would this be the case?
a. MEOS requires NADPH which is generated from NADH
Which of these energy sources takes the longest time to provide ATP for use by the muscle?
c. triglycerides
The role of topoisomerases is to:
b. maintain the cellular DNA in a slightly unwound form
Which of the following statements regarding replication fidelity is not correct?
c. The 5' to 3' exonuclease activity of Pol I is essential for increased fidelity of polymerase activity.
In prokaryotes how does the mismatch repair system identity the strand of DNA which has the wrong base incorporated?
b. The strand with the incorrect base is not methylated.
c. For a brief period following replication the daughter strand is not methylated
Which of the following base substitutions is a transition mutation?
c. G to A
Which of the following enzymes (proteins) is required for replication of the prokaryotic genome?
b. helicase
c. DNA ligase
Which of the following is a transversion mutation?
a. adenine to thymine
c. Guanine to cytosine
Which of the following statements regarding telomeres is correct?
a. Telomeres shorten with each round of replication in all eukaryotic cells.
c. Telomeres are extended by an RNA dependent enzyme.
Which of the following enzyme activities is not needed in the direct repair of a mutation in the DNA sequence?
d. all of the above
Which of the following characteristics are common to topoisomerases and recombinases?
a. they function as endonucleases
c. active tyrosine residues involved in catalysis
What function does the 5' to 3' exonuclease activity of Pol I serve in E. coli?
a. remove the RNA primers used to initiate the lagging strand Okazaki fragments
d. remove the primer on the leading strand