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29 Cards in this Set

  • Front
  • Back

Rapid-acting agents

Lispro (Humalog)
Aspart (Novolog)
Glulisine (Apidra)

Short-acting agents

Regular (Humalog R, Novolin R, Iletin II Regular)

Intermediate-acting agents

NPH (neutral protamine Hagedon)
(Humulin N, Iletin II Lente, Iletin II NPH, Novolin L [Lente], Novolin N [NPH])

Very long-acting agents

Glargine (Lantus)
Detemir (Levemir)

Rapid-acting indications

Used for rapid reduction of glucose level, to treat postpranial hyperglycemia, and/or to prevent nocturnal hypoglycemia

Short-acting indications

Usually administered 20-30 mins before meal; may be taken alone or in combination with longer acting insulin

Intermediate-acting indications

Usually taken after food
Very long-acting indications

Used for basal dose

Rapid-acting onset

5-15 minutes

Short-acting onset

30 mins - 1 hour

Intermediate-acting onset

1-2 hours

Very long-acting onset

(1-2 hours?)


Glargine 4-6 hours


Detemir 2-3 hours

Rapid-acting peak

30 mins - 1.5 hours

Short-acting peak

2-4 hours

Intermediate-acting peak

4-8 hours

Very long-acting peak

Glargine: continuous (no peak)


Detemir relatively flat (6-8 hours)

Rapid-acting duration

3-5 hours

Short-acting duration

4-8 hours

Intermediate-acting duration

10-20 hours

Very long-acting duration

Glargine 20-24 hours


Detemir up to 24 hours (dose-dependent)

Lispro (Humalog)
onset: 10-15 mins
peak: 1 hour
duration: 2-4 hours
Aspart (Novolog)

onset: 5-15 mins
peak: 40-50 mins
duration: 2-4 hours

Glulisine (Apidra)

onset: 5-15 mins
peak: 30 mins - 1 hour
duration: 2 hours

Regular (Humalog R, Novolin R, Iletin II Regular)

onset: 30 mins - 1 hour
peak: 2-3 hours
duration: 4-6 hours

NPH (neutral protamine Hagedorn)

onset: 2-4 hours
peak: 4-12 hours
duration: 16-20 hours

(Humulin N, Iletin II Lente, Iletin II NPH, Novolin L [Lente], Novolin N [NPH])

onset: 3-4 hours
peak: 4-12 hours
duration: 16-20 hours

Glargine (Lantus)

onset: 1 hour
peak: continuous (no peak)
duration: 24 hours

Detemir (Levemir)

onset: 1 hour
peak: continuous (no peak)
duration: 24 hours

T1DM basal bolus %s & amt/bolus

50% Basal, 50% bolus


1U/15g carb for starting bolus dose