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31 Cards in this Set
- Front
- Back
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what mediates fever
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il-1, TNF, PGE2
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what mediates vasodialation
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NO, PGs, Histamine
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transudate
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initial fluid.... a low protein, low specific gravity
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exudate
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high protein, high exudate
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what are the three types of exudate
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fibrinous ... few cells
purulent..... many cells sanguineous.... blood |
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what is the difference between endothelial cell contraction and retraction
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contraction takes place immdiately and is over quickly
retraction is slower and lasts longer |
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mediates contraction
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paf, histamine, bradykinin, luekotrienes
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mediates retraction
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IL-1, INF-gamma, TNF
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describe direct endothelial injury
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immdiated and sustained
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mediates pain
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bradykinin and pge2
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activated endothelial cells procuce
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PGI2 and NO
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adhesion to endothelial walls
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ICAM and VCAM
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translocation through the wall
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PECAM
"peek" through |
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what mediates attachement of phagosomes
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IgG, C3b, collectins
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first phagocyte on scene
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PMN
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replace neutrophils
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monocytes
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monocyte live longer in circulation that in the tissue
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FALSE can live for months in the tissue opposed to one day in circulation
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what is the most importannt microbicidal released by neutrophils
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ROS
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eoisinophils react to....
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allergic reactions and parasites
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mast cells produce
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histamine
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chronic inflammation leads to
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tissue destruction and fibrosis
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cellulitis
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diffuse infliltration of neutrophils with edema
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abscess
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localized liquifative necrosis
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ulcer
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erosion of epithelium exposing CT
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both chronic and acute inflammation may be reversable or fatal
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TRUE
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prostaglandins and leukotrienes both come from
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arachadonic acid
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Increase vascular permeability
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horny boys like pussy cats
histamine, bradykinin leukotrienes paf c5a c53 |
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how do granulomatas heal
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fibrosis
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associated with vasoconstricion and bronchoconstriction
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Leukotriene c d e
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leukotriene b4
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activate leukocyte
has to come b4 .... before |
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vasodialation
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HBP
dialate .... grow hisatmine, bradykinin, prostaglandins |
