Infections Of The Respiratory Tract

Front 1

Respiratory anatomy and defenses

Back 1

Upper Resp. Tract
-Defenses: mucus, macrophages.
-Contains normal microbiota
Lower Resp. Tract
-Defenses:mucus,cilia, macrophages.
Infections of the lower tract are often more serious than upper.

Front 2

Infections of Upper Tract

Back 2

Rhinitis- adenovirus, rhinovirus, respiratory syncitial virus.
Pharyngitis- Fusobacterium necrophorum, Strep. pyogenes.

Front 3

Rhinitis

Back 3

Virulence Factors: attachment proteins; most symptoms induced by host response.
Treatment: for symptoms only.

Front 4

Pharyngitis

Back 4

Virulence Factors: LTA, M protein, hhyaluronic acid capsule, SLS and SLO, super antigens.
Treatment: antibiotics; penicillin (cepalexin for pen. allergic)

Front 5

Infections of Upper AND Lower Tract

Back 5

Seasonal Influenza- Influenza viruses A,B, and C.
Pandemic Influenze- Influenza viruses A,B, and C.

Front 6

Seasonal Influenza

Back 6

Virulence Factors- glycoprotein spikes, overall ability to change genetically.
Treatment: treat symptoms or use anti-virals
-Tamiflu
-Relenza

Front 7

Pandemic Influenza

Back 7

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Front 8

Infections of Lower Tract

Back 8

Community-acquired pneumonia- Strep. pneumonia, Mycoplasma pnemonia.
Nosocomial pneumonia- Klebsiella pneumonia.

Front 9

Community-Acquired pneumonia

Back 9

Virulence Factors: capsule
Treatment: cephalosporin antibiotics- cefotaxime, ceftriaxone

Front 10

Nosocomial pneumonia

Back 10

Virulence Factors: capsule
Treatment: broad-spectrum antibiotics
-penicillins
-cephalosporins