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19 Cards in this Set

  • Front
  • Back

Study of incidents, distribution and control of disease in populatipn

Ediemiology

Ability of microorganism to gain entry into host tissue and bring about disease

Patogenicity

Requirements for pathogen to cause disease (7)

Has to maintain resavoir,


has to get to you,


portal of entry,


adhere to body,


invade immune system,


divide,


has to get out

3 resevoirs

Human, animals, enviroment

2 types human resivoir

Symptamtic, asymptomatic

What is symptomatic

When a person shows signs of disease

What is asymptomatic

Carriers, do not show signs of disease

What is an incubatory carrier

Someone who's infected and will eventually get sick

What is a chronic carrier

Someone who recovered from disease but continues to shed disease causing agent.

8 mode of transmission

Respitory droplet (most common)


Droplet nuclie


Phomite (inanimate object)


Direct body contact


Fecal Oral


Arthropod vectors (insects)


Parental (needle stick)


Food water (has ability to infect.the.most

Most important requirement for infection?

Portal of entry

Steps in invading immune systerm

Hide in host cell


Avoid killing by compliment protein


Avoid destruction by phagtosis


Surviving within phagocyte


Avoids antibodies

What stage does human start getting sick

When microorganism starts to divide and multiply

Gram + and Gram - organism, produced through bacterial metabolism. Very destructive and very SPECIFIC

Extotoxin

Gram - organism. Lippolysaccride, not as specific or destructive

Endotoxin

First line of defense in immune sytsem

Physical barrier, antimicrobial substances, normal flora

2 types of physical barrier

Skin, mucas membrane

4 antimicrobial subatances

Lysozyme


Peroxidase


Lactoferrin


Defensins

What is a microorganism growing on body surfaces of healthy individual

Normal flora