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17 Cards in this Set
- Front
- Back
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What type of HS reaction has the hallmarks of:
delay time time required for the reaction to develop to re-exposusre to Ag recruitment of macros INSTEAD of neutros and extensive tissue damage? |
Type IV HS rxns
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Which T cells are mainly involved responses initiated by Ag specific T cells which inflame by recruiting macros?
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Th1
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What is another name for Type IV cell mediated HS?
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DTH
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What are the target Ags of the type IV HS?
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environmental
self Ags intracellualr pathogens that are hard to clear |
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What two main events must occur to produce a DTH?
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sensitization and Re-exposusre
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In what AI disease type IV HS rxn does P3 protein of peripheral nerve myelin undergo destruction?
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Guillain-Barre Syndrome
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In contact hypersensitvity, what often acts as the senstizing substance?
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often a hapten that complexes with skin proteins
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To which T cells do the dendritic APCs in contact hypersensitvity present the proteins from the hapten complex?
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CD4+ cells
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What is the name of chronic DTH reaction against mycobacterial agents?
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granulomatous inflammation
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Besisdes Myco. TB, what else can cause granulomatous inflammation?
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fungi
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does allograft rejection occur in acute AND chronic rejection?
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both
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What does a positive DTH skin test reveal?
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only means that the person has been sensitized
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What is the term fo a person haveing no reaction to a DTH skin test?
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anergic
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does a + TB test rule in infection?
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No
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When is the DTH TB test checked?
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24, 48, 72 hours
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How long does it take to develop a wheal and flare?
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15 min
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How long does it take to develop and arthus reaction?
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5-12 ours
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