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29 Cards in this Set
- Front
- Back
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What are the two forms that adaptive immunity can take?
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-Cell Mediated / Cellular Immunity
-Humoral Immunity |
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Describe Cellular Immunity?
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Immunity mediated by T cells (T helper cells and Cytotoxic T cells)
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Describe Humoral Immunity?
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Immunity mediated by B cells that secrete antibody
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What are primary lymphoid organs?
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Where immune cells arise (Bone marrow and Thymus)
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What are the secondary lymphoid organs?
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Where adaptive immune responses are generated
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Where are neutrophils stored?
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In bone marrow
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Are B cells or T cells closest to the arteriole in the spleen?
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T cells are closest to the arteriole
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What is an M cell? Where is it found?
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An M cell is a rudimentary brush border cell found in the gut, that secretes much less glycocalyx and is thus much more susceptible to pathogens. It is found in Pyers Patches
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What is the purpose of the M cell?
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Its heightened susceptibility allows it to take in / sample more pathogens for the immune system.
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What is the most common leukocyte?
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Neutrophils
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What is the least common leukocyte?
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Eosinophils and basophils
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What are the innate immune cells?
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MMM NN BED
-Macrophages -Monocytes -Mast Cells -Neutrophils -NK cells -Basophils -Eosinophils -Dendritic Cells |
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What are the Adaptive immune cells?
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T cells and B cells
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Discuss Macrophages
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-Phagocytosis and activation of bacterialcidal mechanisms
-Antigen presentation -Cytokines Secretion |
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What does the release of cytokines accomplish?
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Promotes T and B cell responses, antiviral responses, etc, etc
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Describe Monocytes.
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Phagocytes that can differentiate into macrophages and dendritic cells.
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Describe Mast Cells.
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Initiate an inflammatory response by releasing histamines and recruiting eosinophils and basophils
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Describe Neutrophils.
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Phagocytes that engulf and kill pathogens. THey are stored in bone marrow, and release to the site of an infection
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Describe Natural Killer cells.
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They release lytic granules that kill virus infected cells and tumor cells
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Describe Basophils.
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RARE granulocytes the initiate the production of IgE antibodies (allergy)
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Describe Eosinophils.
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(similiar to basophils) Destroy antibody coated parasites
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Describe Dendritic cells.
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There are two types: Myeloid and Plasmacytoid
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What is so great about denditic cells?
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They link innate and adaptive immunities!
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Where do myeloid dendritic cells exist?
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They cirrculate in tissues and capture pathogens and antigens
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Where do plasmacytoid dendritic cells exist?
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They cirrculate in the blood and detect viruses
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What is the major activated function of dendritic cells?
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Antigen presentation!
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What are the two types of adaptive immune cells?
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T cells and B cells
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What are the two types of T cells?
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T helper cells (cell mediated immunity) and Cytotoxic T cells (specifically target SPECIFIC infected cells)
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What is the major function of B cells?
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To secrete antibodies to mediate humoral immunity: (MEAD G)
-IgM -IgE -IgA -IgD -IgG |
