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18 Cards in this Set
- Front
- Back
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Chemotactic for neutrophils
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CXCL8
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Enhances NADPH Oxidase Activity
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IFNgama, TNF
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Down regulates iNOS
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TGFbeta
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Chemotactic for monocytes
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CCL2
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Down regulates production of Type 2 cytokines
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IFNgamma
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Activates iNOS
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IFNgamma, TNF
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Shifts Th0 differentiation to Th1
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IFNgamma
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Enhances Class I MHC expression
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IFN alpha/beta, IFN gamma
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Chemotactic for Eosinophils
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CCL11
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Enhances expression of Class II MHC
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IFN gamma
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Req. to differentiate Th0 to a/i Tregs
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TGFbeta
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Triggers production of enzymes that interfere with replication of some viruses
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IFN alpha/beta
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Activates inducible NO synthase (does not need other signal
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IFNgamma, TNF
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Enhances NADPH oxidase activity
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IFNgamma, TNF
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Role in differentiation of precursor cells to monocytes but not other lineages
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M-CSF
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In the presence of a 2nd signal actives inducible NO synthase
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TNF, IFNgamma
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Inhibits inducible NO synthase (iNOS) best
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TFGbeta
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Role in diff of eosinophils but not other lineages
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IL5
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