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27 Cards in this Set
- Front
- Back
*What causes peripheral lymphoid tissues to become populated with B & T cells
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Chemokines
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Describe spacial and temporal regulation of B cell activation
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a
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What is the role of the medullary area?
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a
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What is the role of the B cell area?
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a
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What is the role of the T cell area?
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a
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What is the role of the primary focus?
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a
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What is the role of the germinal center?
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a
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What role do follicular dendritic cells play in humoral immunity?
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a
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What are some characteristics of follicular dendritic cells?
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a
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In regards to BCR antigens - what are the three different classes?
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Thymus dependent
TI-1 TI-2 |
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What is the outcome of stimulation by a thymus dependent antigen?
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a
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What is the outcome of stimulation by a TH-1 antigen?
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a
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What is the outcome of stimulation by a TH-2 antigen?
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a
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What are some important molecules involved in thymus dependent B cell activation?
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Signal 1
Signal 2 CD40:CD40L |
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A _________ B cell differentiates into a ___________ which differentiates into a ____________
In the event an antigen reoccurs _________ B cells can be activated |
Resting, Plasma blast, Plasma Cell
Memory |
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Describe linked recognition
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a
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Describe passive immunity
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a
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Describe somatic hypermutation
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a
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Describe class switching
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a
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What are some key characteristics of IgM?
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aa
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What is the first immunoglobulin produced?
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IgM
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What are some key characteristics of IgG?
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a
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What are some key characteristics of IgD?
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a
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What are some key characteristics of IgA?
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a
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What are some key characteristics of IgE?
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a
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Name three effector functions of antibodies
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Neutralization, opsonization, complement activation, ADCC, mast cell activation
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What is ADCC
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Antibody-dependent Cell cytotoxicity
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