Immunology - In-Class Quizzes

Front 1

contains the light chain constant region

Choose Either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 1

Fab region (above disulfide bond)

Front 2

Determines biological function

Choose Either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 2

Fc region (below disulfide bond)

Front 3

Determines specificity

Choose Either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 3

Fab region (above disulfide bond)

Front 4

Contains the antigen binding site

Choose Either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 4

Fab region (above disulfide bond)

Front 5

Determines isotype

Choose Either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 5

Fc region (below disulfide bond)

Front 6

Contains the heavy chain variable region

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 6

Fab region (above disulfide bond)

Front 7

Degraded when exposed to pepsin, but not to papain

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 7

Fc region (below disulfide bond)

Front 8

Determines allotype

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 8

Fc region (below disulfide bond)

Front 9

Determines avidity

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 9

Fab region (above disulfide bond)

Front 10

Contains the complementary determining regions

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 10

Fab region (above disulfide bond)

Front 11

Determines affinity

Choose either:
Fab region (above disulfide bond)
Fc region (below disulfide bond)

Back 11

Fab region (above disulfide bond)

Front 12

FCγR

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 12

a) Phagocyte

Front 13

C3a

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 13

d) Mast Cell

Front 14

FCεR

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 14

c) Eosinophil
d) Mast Cell

Front 15

CR1

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 15

a) phagocyte

Front 16

Engulf microbes outside cells

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 16

a) Phagocyte

Front 17

Class I MHC

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 17

all

Front 18

Defensins

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 18

a) Phagocyte

Front 19

KIR

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 19

b) Natural Killer Cell

Front 20

kills helminths

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 20

c) Eosinophil
d) Mast Cell

Front 21

PPRR

Possible answers:
a) Phagocyte
b) Natural Killer Cell
c) Eosinophil
d) Mast Cell

Back 21

a) Phagocyte

Front 22

Co-dominant Expression

Possible answers:
a) MHC I
b) MHC II

Back 22

MHC I
MHC II

Front 23

expressed on virtually all nucleated cells

Possible answers:
a) MHC I
b) MHC II

Back 23

MHC I

Front 24

displays antigenic fragments destroyed by the proteasome

Possible answers:
a) MHC I
b) MHC II

Back 24

MHC I

Front 25

expressed on antigen presenting cell

Possible answers:
a) MHC I
b) MHC II

Back 25

MHC II

Front 26

presents antigenic peptides to CD8 T cells

Possible answers:
a) MHC I
b) MHC II

Back 26

MHC I

Front 27

presents antigenic peptides to CD4 T cells

Possible answers:
a) MHC I
b) MHC II

Back 27

MHC II

Front 28

Displays antigenic fragments destroyed within the phagolysosome

Possible answers:
a) MHC I
b) MHC II

Back 28

MHC II

Front 29

Murine H2-K,H2-D & H2-L

Possible answers:
a) MHC I
b) MHC II

Back 29

MHCI

Front 30

HLA DR10

Possible answers:
a) MHC I
b) MHC II

Back 30

MHC II

Front 31

HLA A4

Possible answers:
a) MHC I
b) MHC II

Back 31

MHC I

Front 32

Activates complement classical pathway

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 32

IgG and IgM

Front 33

Mucosal immunity

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 33

IgA

Front 34

Helmnith infections

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 34

IgE

Front 35

Opsonin

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 35

IgG

Front 36

High concentrations in colostrum and breast milk

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 36

IgA

Front 37

Covalent attachment J chain

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 37

IgM and IgA

Front 38

First antibody secreted in primary immune response

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 38

IgM

Front 39

ADCC

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 39

IgG

Front 40

Crosses the placenta

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 40

IgG

Front 41

Isohemagluttinin

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 41

IgM

Front 42

Allergies

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 42

IgE

Front 43

Neutralize virus + toxins

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 43

IgG

Front 44

Kappa constant region

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 44

all

Front 45

Four subclasses

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 45

IgG

Front 46

Secretory component

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 46

IgA

Front 47

Mast cells and basophils

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 47

IgE

Front 48

Highest conc in serum

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 48

IgG

Front 49

Lambda light chain

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 49

all

Front 50

Largest half life

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 50

IgG

Front 51

Exists as monomer on cell surface

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 51

all

Front 52

Serum levels in newborns same as adults

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 52

IgG

Front 53

Reaginic antibody
(allergic activity)

Possible answers:
a) IgG
b) IgM
c) IgA
d) IgE
e) IgD

Back 53

IgE

Front 54

Hematopoeisis

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 54

IL3, IL5, GM-CSF, G-CSF, M-CSF

Front 55

Inhibits iNOS (most effective)

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 55

TGFβ

Front 56

Role in differentiation of precursor cells to granulocytes.

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 56

G-CSF

Front 57

Enhances action of NADPH oxidase

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 57

IFNγ

Front 58

Role in differentiation of Eosinophils

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 58

IL-5

Front 59

Induces NOS

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 59

IFNγ

Front 60

In the presence of a second signal induces inducible NOS.

Possible answers:
a) IL3
b) IL5
c) GM-CSF
d) G-CSF
e) M-CSF
f) TGFb
g) TNF
h) IL-4
i) IL-10
j) IFN-gamma

Back 60

TNF

Front 61

All the following are characteristics of immunogenic molecules EXCEPT

a. chemically complex
b. only present in human species
c. usually proteins
d. high molecular weight
e. foreign

Back 61

b. only present in human species

Front 62

Which one of the following is not a receptor-ligand pair
a. CD80/CD152
b. CD4/ MHC Class II
c. CD11a/ CD18 : ICAM-2
d. CD40L/ CD154
e. CD80/ CTLA-4

Back 62

d. CD40L/ CD154

Front 63

A process that occurs after antigen-induced B cell activation and leads to a different heavy chain constant region

Possible answers:

a)      allelic exclusion
b)      isotype switching
c)      somatic recombination
d)      somatic mutation
e)      alternative splicing
f)        tolerance induction

Back 63

Isotype Switching

Front 64

A process that occurs during B cell maturation. It leads to the elimination or inactivation of B cells that are autoreactive.

Possible answers:

a) allelic exclusion
b) isotype switching
c) somatic recombination
d) somatic mutation
e) alternative splicing
f) tolerance induction

Back 64

tolerance induction

Front 65

A process that occurs during B cell maturation that leads to the expression of both IgM and IgD on the cell surface.

Possible answers:

a) allelic exclusion
b) isotype switching
c) somatic recombination
d) somatic mutation
e) alternative splicing
f) tolerance induction

Back 65

alternative splicing

Front 66

A process that occurs after antigen induced B cell activation and leads to a different variable region because of mutations in the hypervariable region ; also called affinity maturation.

Possible answers:

a)      allelic exclusion
b)      isotype switching
c)      somatic recombination
d)      somatic mutation
e)      alternative splicing
f)        tolerance induction

Back 66

somatic mutation

Front 67

A process by which gene segments are excised and the remaining gene segments ligated

Possible answers:

a)      allelic exclusion
b)      isotype switching
c)      somatic recombination
d)      somatic mutation
e)      alternative splicing
f)        tolerance induction

Back 67

somatic recombination

Front 68

A term used to define a process that leads to expression of one allele in cells that contain two different alleles at a particular locus

Possible answers:

a)      allelic exclusion
b)      isotype switching
c)      somatic recombination
d)      somatic mutation
e)      alternative splicing
f)        tolerance induction

Back 68

allelic exclusion

Front 69

Transcription of Rag-1 and Rag-2

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 69

proB cell stage

Front 70

Initial expression of CD20

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 70

preB cell stage

Front 71

Tolerance induction

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 71

Immature B cell stage

Front 72

Somatic recombination of the variable region (heavy chain)

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 72

Pre-B Cell stage

Front 73

Initial expression of IgM on the B cell surface

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 73

Immature B Cell Stage

Front 74

Initial expression of CD19

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 74

Pro-B Cell stage

Front 75

Transcription of terminal deoxynucleotide transferase

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 75

Pro-B cell stage

Front 76

allelic exclusion

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 76

Pre-B Cell Stage

Front 77

Alternative Splicing

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 77

Naïve mature B cell stage

Front 78

Initial expression of IgD on the cell surface.

Possible answers:
a. proB cell stage
b. preB cell stage
c. Immature b cell stage
d. naïve mature B cell stage

Back 78

Naïve mature B cell stage

Front 79

S-protein

Possible answers:

a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 79

MAC
S-protein, vitronectin, C5b,6,7,8,9, CD59 and HRF is MAC

Front 80

C5b, 6, 7, 8, 9

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 80

MAC
S-protein, vitronectin, C5b,6,7,8,9, CD59 and HRF is MAC

Front 81

Vitronectin

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 81

MAC
S-protein, vitronectin, C5b,6,7,8,9, CD59 and HRF is MAC

Front 82

Factor H

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 82

C3 convertase Alternative Pathway

Front 83

Properdin

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 83

C3 convertase Alternative Pathway

Front 84

Decay accelerating factor (DAF)

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 84

C3 convertase Alternative Pathway
C3 convertase Classical Pathway

Front 85

Cleaves C3

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 85

C3 convertase Alternative Pathway
C3 convertase Classical Pathway

Front 86

C3bBbC3b

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 86

C5 convertase Alternative Pathway

Front 87

Homologous Restriction Factor (HRF)

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 87

MAC

Front 88

C4bp

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 88

C3 convertase Classical Pathway
Anything C4 is classical pathway!

Front 89

C4b2a

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 89

C3 convertase Classical Pathway
Anything C4 is classical pathway!

Front 90

CD59

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 90

MAC

Front 91

C4b2aC3b

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 91

C5 convertase CP
Anything C4 is classical pathway!

Front 92

Factor I

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 92

C3 convertase Alternative Pathway
C3 convertase Classic Pathway

Front 93

allelic exclusion

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 93

B cell differentiation and maturation in bone marrow

Front 94

somatic recombination

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 94

B cell differentiation and maturation in bone marrow

Front 95

somatic mutation

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 95

B cell differentiation antigen induced in an immune response

Front 96

alternate splicing

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 96

B cell differentiation and maturation in bone marrow

Front 97

tolerance induction

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 97

B cell differentiation and maturation in bone marrow

Front 98

Isotype switching

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 98

B cell differentiation antigen induced in an immune response

mutation, switching, and maturation all induced in an immune response

Front 99

Affinity maturation

Possible Answers
a. B cell differentiation and maturation in bone marrow
b. B cell differentiation antigen induced in an immune response

Back 99

B cell differentiation antigen induced in an immune response

mutation, switching, and maturation all induced in an immune response

Front 100

tolerance induction

Possible Answers
a. B cell differentiation and maturation in bone marrow

b. B cell differentiation antigen induced in an immune response

Back 100

B cell differentiation and maturation in bone marrow

Front 101

CD2

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 101

T-cells (all)

Front 102

LFA-1

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 102

T-cells (all)

Front 103

LFA-3

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 103

Antigen Presenting Cells

Front 104

ICAM-1

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 104

Antigen Presenting Cells

Front 105

CD28

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 105

T-cells (all)

Front 106

MHC Class II

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 106

Antigen Presenting Cells

Front 107

CD154

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 107

T-cells (all)

CD154 = CD40L

Front 108

CD8

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 108

T-cells (subset)

Front 109

CD80 (B7-1)

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 109

Antigen Presenting Cell

Front 110

CD86 (B7-2)

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 110

Antigen Presenting Cell

Front 111

CD-40L

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 111

T-cells (all)

Front 112

CD11a

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 112

T-cells (all)

CD11a = LFA-1

Front 113

CD18

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 113

T-cells (all)

Front 114

CD40

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 114

Antigen Presenting Cells

Front 115

CD4

Choose either:
T-cells (all)
T-cells (subset)
Antigen Presenting Cells

Back 115

T-cell (subset)

Front 116

Secreted by Th-17

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 116

IL-17A, IL-17F, IL-21

Front 117

Amplification factor for Th17 cells

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 117

IL-21

Front 118

Downregulates iNOS

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 118

IL-4, IL-10

Front 119

Induces secretion of IFNγ by NK cells

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 119

IL-12

Front 120

Downregulates IL-12 production

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 120

IL-10

Front 121

Stimulus for secretion of C-reactive proteins from hepatocytes

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 121

IL-6

Front 122

Shifts Th0 differentiation towards Th2

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 122

IL-4

Front 123

Required for Isotype switching to Isotype E

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 123

IL-4

Front 124

Role in T-cell development in the thymus

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 124

IL-7

Front 125

Downregulates production of Type 1 Cytokines

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 125

IL-4 and IL-10

Front 126

Eosinophil differentiation and recruitment from the bone marrow

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 126

IL-5

Front 127

Required for immune response against helminths

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 127

IL-4 - Isotype switching to IgE
IL-5 - eosinophil differentiation

Front 128

Role in hematopoiesis for both myeloid and lymphoid progenitor cell generation

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 128

IL-3

Front 129

Growth factor for T cells

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 129

IL-2

Front 130

At [high] will convert NK cells to LAK cells (more potent killers)

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 130

IL-2

Front 131

Secreted by activated macrophages and acts in both a paracrine and autocrine manner to activate or enhance the activation of macrophages

Choose from the following:
IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12, IL-17A, IL-17F, IL-21

Back 131

IL-1

Front 132

Chemotactic for neutrophils

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 132

CXCL8

CXCL8 = IL-8

Front 133

Enhances NADPH Oxidase Activity

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 133

IFNγ, TNF

Front 134

Down regulates iNOS

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 134

TGFβ

Front 135

Chemotactic for monocytes

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 135

CCL2

CCL2 = MCP-1

Front 136

Down regulates production of Type 2 Cytokines

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 136

IFNγ

Front 137

Activates iNOS

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 137

IFNγ, TNF

Front 138

Shifts Th0 differentiation to Th1

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 138

IFNγ

Front 139

Enhances Class I MHC Expression

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 139

IFNα/β, IFNγ

Front 140

Chemotactic for eosinophils

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 140

CCL11

CCL11 = Eotaxin

Front 141

Enhances expression of Class II MHC

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 141

IFNγ

Front 142

Required for differentiation fof Th0 to a/i Tregs

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 142

TGFβ

Front 143

Triggers production of enzymes that interfere with replication of some viruses

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 143

IFNα/β

Front 144

2-5 oligoadenylate synthetase

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 144

IFNα/β

Front 145

inhibition of T cell proliferation

Possible Answers:
IFNγ, TNF, TGFβ, IFNα/β, CXCL8, CCL2, CCL11

Back 145

IFNα/β

Front 146

C1 Inhibitor

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 146

C3 Convertase Classical Pathway

Front 147

Factor B

Possible answers:
a. C3 convertase Alternative Pathway
b. C3 convertase Classic Pathway
c. C5 convertase Alternative Pathway
d. C5 convertase Classic Pathway
e. MAC

Back 147

C3 Convertase Alternative Pathway

Front 148

GM-CSF

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 148

Macrophage

all CSF = Macrophage.
GM = Macrophage & Tcell

Front 149

IL-1

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 149

Macrophage

Front 150

G-CSF

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 150

Macrophage.

all CSF = Macrophage

Front 151

IL-7

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 151

Bone Marrow Stromal Cell

Front 152

IL-12

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 152

Dendritic Cell
Macrophage

Front 153

TNF

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 153

Macrophage

Front 154

IL-4

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 154

Mast Cells

Front 155

M-CSF

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 155

Macrophage

All CSF = Macrophage

Front 156

IL-5

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 156

Mast Cells

Front 157

IFNγ

Possible Answers:
Bone Marrow Stromal cells
Dendritic Cells
Natural Killer cells
Macrophages
Mast Cells

Back 157

Natural Killer Cell

Front 158

VCAM-1

Possible Answers:
LFA-1, MAC-1, VLA-4

Back 158

VLA-4

VLA-4 = CD49d & CD29

Front 159

CD11a-CD18

Possible Answers:
LFA-1, MAC-1, VLA-4

Back 159

LFA-1

CD11a-CD18 is another name for LFA-1

Front 160

CD11b-CD18

Possible Answers:
LFA-1, MAC-1, VLA-4

Back 160

MAC-1

MAC-1 is another name for CD11b-CD18

Front 161

ICAM-1

Possible Answers:
LFA-1, MAC-1, VLA-4

Back 161

LFA-1 and MAC-1

Front 162

Kill virally infected cells

Possible Answers:
a. Th1 cells
b. Th2 cells
c. Both Th1 and Th2 cells
d. CTL
e. All of the above

Back 162

CTL

Front 163

Secrete cytokines required for activation of macrophages

Possible Answers:
a. Th1 cells
b. Th2 cells
c. Both Th1 and Th2 cells
d. CTL
e. All of the above

Back 163

Th1 cells

Front 164

Activation via the TCR complex leads to the phosphorylation of ITAMS

Possible Answers:
a. Th1 cells
b. Th2 cells
c. Both Th1 and Th2 cells
d. CTL
e. All of the above

Back 164

e. All of the above

Front 165

Secrete cytokines that inhibit IL-12 production by dendritic cells

Possible Answers:
a. Th1 cells
b. Th2 cells
c. Both Th1 and Th2 cells
d. CTL
e. All of the above

Back 165

b. Th2 cells

Front 166

May differentiate into memory cells

Possible Answers:
a. Th1 cells
b. Th2 cells
c. Both Th1 and Th2 cells
d. CTL
e. All of the above

Back 166

e. All of the above