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31 Cards in this Set

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The myeloid progenitor gives rise to the myeloid lineage of cells which include?
1-granulocyte which gives rise to neutrophil, eosinophil, and basophil. 2-unknown precursor which gives rsie to mast cell and monocyte. The monocyte then gives rise to dendritic cell and macrophage.
The erythroid progenitor gives rise to erythroid lineage which includes which cells?
1-megakaryocyte which then gives rise to platelets. 2-erythroblast which then gives rise to erythrocyte.
Megakaryocytes
1-means cell with giant nucleus.2-permanent residents of thebone marrow.3-platelets which are small packets of membrane bound cytoplasm break off these cells.4-giant cells that arise from the fusion of multiple precursor cells and have nuclei containing multiple sets of chromosomes.5-wound repair.
Erythroblast
Produce erythrocytes which are oxygen transporting.
Granulocytes
1-contain cytoplasmic granules that contain reactive substances that kill microorganisms.2-AKA polymorphonuclear leukocytes because they have an irregular shaped nuclei with two to five lobes.3-becomes neutrophil, eosinophil, and basophil.
Neutrophil
1-short lived phagocytic.2-most abundant of granulocytes and WBCs.3-most numerous and lethal phagocyte.4-can work in anaerobic conditions and prevail in damged tissue.5-form pus.
Eosinophil
1-second most abundant granulocyte.2-defends against helminth worms and other intestinal parasites.3-not phagocytic.4-dumps granules at specifically what trying to kill.5-poison of granules not good for tissue nearby.6-has receptors that will hold antibodies onto itself and wait to be stimulated.
Basophil
1-least abundant granulocyte.2-less than 1% of peripheral blood.3-involved in allergic rxn and inflammation but not much is known about them.
Cells capable of presenting antigens?
dendritic, B-cells, and macrophages.
All WBCs are____ while lymphocytes are only___?
leukocytes, B-Cells and T-Cells
What cells are educated in the bone marrow?
B-Cells
What cells are educated in the thymus?
T-Cells
What is the primary lymphoid organ?
thymus
What are the secondary lymphoid organs?
Places that lymphocytes go to be activated and include lymph nodes, spleen, peyer's patch in small intestine, adenoid, and tonsil.
What makes up lymph?
The ECF and liquid portion of the blood (WBC may be present) and interconnects with the blood.
What is the primary job once inside the lymph node?
Primary job is to find antigen. If they find antigen they otherwise if no antigen is found they leave through the lymphatic system and meet up with the blood again later.
What is the primary job once inside the lymph node?
Primary job is to find antigen. If they find antigen they otherwise if no antigen is found they leave through the lymphatic system and meet up with the blood again later.
What cell is located in the follicles?
B-Cells are located here and when activated they will begin to divide which causes the swelling.
What cell is located in the follicles?
B-Cells are located here and when activated they will begin to divide which causes the swelling.
What happens when they recognize and antigen?
They make copies of themselves.
What happens when they recognize and antigen?
They make copies of themselves.
What two things do activated T-Cells do?
1-leave through the lymphatic system to fight infection. 2-some activate B-cells to provide antibodies. Antibodies then leave through the efferent lymphatic system.
What two things do activated T-Cells do?
1-leave through the lymphatic system to fight infection. 2-some activate B-cells to provide antibodies. Antibodies then leave through the efferent lymphatic system.
Red pulp of spleen
filters RBC
Red pulp of spleen
filters RBC
White pulp
Secondary lymphoid organ to blood. Loosing your spleen increases your chances of infection especially blood born.
M Cells
M Cells of the gut epithelial wall deliver pathogens from teh luminal side of the gut mucosa to lymphoid tissue within the gut.
GALT
gut-assosciated lymphoid tissues
BALT
Bronchial-assosciated lympoid tissue
MALT
Mucosal-assosciated lymphoid tissue
Complement
About 20 proteins make up this system. Complements are always present. Once a complement cleaves it will insert itself on the pathogen. A complement on a pathogen is like a beacon making the immune system notice. Neutrophils have receptors specific for complements. Faster and better with complement.