Immunology Chapter 1 Innate And Adaptive Immunity

Front 1

The myeloid progenitor gives rise to the myeloid lineage of cells which include?

Back 1

1-granulocyte which gives rise to neutrophil, eosinophil, and basophil. 2-unknown precursor which gives rsie to mast cell and monocyte. The monocyte then gives rise to dendritic cell and macrophage.

Front 2

The erythroid progenitor gives rise to erythroid lineage which includes which cells?

Back 2

1-megakaryocyte which then gives rise to platelets. 2-erythroblast which then gives rise to erythrocyte.

Front 3

Megakaryocytes

Back 3

1-means cell with giant nucleus.2-permanent residents of thebone marrow.3-platelets which are small packets of membrane bound cytoplasm break off these cells.4-giant cells that arise from the fusion of multiple precursor cells and have nuclei containing multiple sets of chromosomes.5-wound repair.

Front 4

Erythroblast

Back 4

Produce erythrocytes which are oxygen transporting.

Front 5

Granulocytes

Back 5

1-contain cytoplasmic granules that contain reactive substances that kill microorganisms.2-AKA polymorphonuclear leukocytes because they have an irregular shaped nuclei with two to five lobes.3-becomes neutrophil, eosinophil, and basophil.

Front 6

Neutrophil

Back 6

1-short lived phagocytic.2-most abundant of granulocytes and WBCs.3-most numerous and lethal phagocyte.4-can work in anaerobic conditions and prevail in damged tissue.5-form pus.

Front 7

Eosinophil

Back 7

1-second most abundant granulocyte.2-defends against helminth worms and other intestinal parasites.3-not phagocytic.4-dumps granules at specifically what trying to kill.5-poison of granules not good for tissue nearby.6-has receptors that will hold antibodies onto itself and wait to be stimulated.

Front 8

Basophil

Back 8

1-least abundant granulocyte.2-less than 1% of peripheral blood.3-involved in allergic rxn and inflammation but not much is known about them.

Front 9

Cells capable of presenting antigens?

Back 9

dendritic, B-cells, and macrophages.

Front 10

All WBCs are____ while lymphocytes are only___?

Back 10

leukocytes, B-Cells and T-Cells

Front 11

What cells are educated in the bone marrow?

Back 11

B-Cells

Front 12

What cells are educated in the thymus?

Back 12

T-Cells

Front 13

What is the primary lymphoid organ?

Back 13

thymus

Front 14

What are the secondary lymphoid organs?

Back 14

Places that lymphocytes go to be activated and include lymph nodes, spleen, peyer's patch in small intestine, adenoid, and tonsil.

Front 15

What makes up lymph?

Back 15

The ECF and liquid portion of the blood (WBC may be present) and interconnects with the blood.

Front 16

What is the primary job once inside the lymph node?

Back 16

Primary job is to find antigen. If they find antigen they otherwise if no antigen is found they leave through the lymphatic system and meet up with the blood again later.

Front 17

What is the primary job once inside the lymph node?

Back 17

Primary job is to find antigen. If they find antigen they otherwise if no antigen is found they leave through the lymphatic system and meet up with the blood again later.

Front 18

What cell is located in the follicles?

Back 18

B-Cells are located here and when activated they will begin to divide which causes the swelling.

Front 19

What cell is located in the follicles?

Back 19

B-Cells are located here and when activated they will begin to divide which causes the swelling.

Front 20

What happens when they recognize and antigen?

Back 20

They make copies of themselves.

Front 21

What happens when they recognize and antigen?

Back 21

They make copies of themselves.

Front 22

What two things do activated T-Cells do?

Back 22

1-leave through the lymphatic system to fight infection. 2-some activate B-cells to provide antibodies. Antibodies then leave through the efferent lymphatic system.

Front 23

What two things do activated T-Cells do?

Back 23

1-leave through the lymphatic system to fight infection. 2-some activate B-cells to provide antibodies. Antibodies then leave through the efferent lymphatic system.

Front 24

Red pulp of spleen

Back 24

filters RBC

Front 25

Red pulp of spleen

Back 25

filters RBC

Front 26

White pulp

Back 26

Secondary lymphoid organ to blood. Loosing your spleen increases your chances of infection especially blood born.

Front 27

M Cells

Back 27

M Cells of the gut epithelial wall deliver pathogens from teh luminal side of the gut mucosa to lymphoid tissue within the gut.

Front 28

GALT

Back 28

gut-assosciated lymphoid tissues

Front 29

BALT

Back 29

Bronchial-assosciated lympoid tissue

Front 30

MALT

Back 30

Mucosal-assosciated lymphoid tissue

Front 31

Complement

Back 31

About 20 proteins make up this system. Complements are always present. Once a complement cleaves it will insert itself on the pathogen. A complement on a pathogen is like a beacon making the immune system notice. Neutrophils have receptors specific for complements. Faster and better with complement.