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31 Cards in this Set
- Front
- Back
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Which elution method is ideal in the investigation of ABO hemolytic disease of the fetus and newborn?
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Freeze thaw
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What describes the principle of the Kleihauer-Betke test?
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Fetal hemoglobin is resistant to acid elution and remains in the cell to stain pink, whereas adult cells appear as ghost cells
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What are the goals of an exchange transfusion?
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Correct anemia, remove of conjugated hemoglobin, ABs
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Why is reverse grouping omitted in the neonatal period for ABO testing?
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Newborns do not produce their own antibody until about 4 months
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Which tests are performed to identify the cause of suspected hemolytic disease of the fetus and newborn?
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ABO grouping, D testing, DAT
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Common characteristics of ABO hemolytic disease of the fetus and newborn
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weak positive DAT, mild clinical symptoms, Antibodies on the infant cells is Anti- A,B
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Which antibodies have been known to cause hemolytic disease of the fetus and newborn?
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L,k,S NOT Anti-Lea
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A group O, D-positive mother gave birth to an A-negative infant. After 24 hours, the newborn's bilirubin level rose to 19 mg/dL. A direct antiglobulin test performed on the cord blood specimen was positive with anti-lgG. What is the most probable antibody causing this?
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Anti-A,B
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Anti-D in the serum of a third-trimester pregnant woman with a titer of 16 is indicative of:
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Active immunization
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Rh immune globulin should be given within how many hours following delivery?
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72 hours
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A 300-gg dose of Rh immune globulin contains sufficient anti-D to protect against how much whole blood?
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30 mL
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The rosette test
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is valid only if the mother is D-negative and infant is D-positive
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In which type of hemolytic disease of the fetus and newborn is the first-born affected?
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ABO
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A weakly reactive anti-D was detected in a sample from a D-negative mother one day following delivery of a D-negative baby. Based on these results the lab should:
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Review records for prenatal RH immunoglobulin administration
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How often can a person donate a unit of whole blood for a directed donation?
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8 weeks
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Blood collected from a therapeutic phlebotomy is:
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acceptable for inventory under certain Food and Drug Administration guidelines
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Which type of autologous donation procedure is the most common for most types of surgery?
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Preoperative Donation
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What contributes to permanent rejection status of a donor?
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Confirmed positive test for hepatitis B surface antigen 10 years previously
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What is a cause for temporary deferment of a whole blood donor?
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Not Aspirin ingestion 12 hours previously
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When would autologous donors may not donate?
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are on antibiotics for an infection
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Allogeneic whole blood donors may donate every days.
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56
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If during the donor screening process, the potential donor's blood drop sinks to the bottom of the copper sulfate solution within 15 seconds. What is the interpretation of this test?
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The donor has an acceptable hemoglobin and hematocrit to donate
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How long must a donor wait to donate red blood cells again following a 2-unit red blood cell apheresis donation?
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16 weeks
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A 58-year-old woman revealed that she had experimented with intravenous drugs as a teenager. What would be the acceptable deferral period, if any, for this potential donor?
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She is indefinite/permanent deferral
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If a prospective donor has participated in a plasmapheresis program, how long must he or she wait to donate whole blood?
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48 hours
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How long does it take to replace the fluid lost from giving whole blood following donation?
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72 hours
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Why is it necessary to mix the unit frequently during the donation process?
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Avoid blood clots by mixing the anticoagulant with the blood
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What is the minimum hemoglobin level for a potential allogeneic donor?
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12.5 g/dL
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What is the purpose of a "diversion pouch" that is used when collecting blood from a donor?
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prevent potential contamination with epidermal cells and potential bacteria entering the donor unit.
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What is the minimum height and weight requirement for a 21-year-old college student who wishes to participate in the "double red" program at the local blood center by donating red blood cells collected by apheresis.
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5'5" 150 lbs
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Which results would exclude a donor from donating?
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HPV 1 weak ago
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