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14 Cards in this Set
- Front
- Back
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Primary or Congenital
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genetic defects
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Secondary or Aquired
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malnutrition
cancer drugs |
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Toll like receptors
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well conserved across species
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deficient humoral immunity
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succeptibility to pyogenic bacteria
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XLA
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bruton tyrosine kinase deficiency prevents B cell maturation
low levels of all anti bodies |
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Hyper IgM
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loss of CD40 .... prevents T cell from communicating with B cell to go through isotope switching..... only IgM is produced
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deficient cell mediated immunity
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results in increased succeptibility to viruses and other intracellular pathogens
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treatin humoral deficiencies
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routine prophylactic antibiotics and or/ gamma globulin
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Degeogre's Syndrome
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thymus never develops..... far fewer T cells
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XSCID
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few or no T cells and NK cells;
B cells that do not function properly |
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HIV 1st phase of decay
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CD4+ T cells
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HIV 2nd phase of decay
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monocytes, macrophages
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HIV 3rd phase of decay
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memory CD4+ cells
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when is it AIDS
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depletion of CD4+ T cells; destruction of lymphoid tissue
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