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19 Cards in this Set
- Front
- Back
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adaptive immunity
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the part of the immune system that is specific and has memory (T and B cells)
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antibodies
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molecules that are secreted by plasma cells; bind to antigen in a specific way
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antigen
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molecules that have specific sequences to which adaptive responses can be generated
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antigenicity
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a property of molecules to which an adaptive immune response can be generated
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antigenic determinant
determinant epitope |
a particular component of an antigen that is recognized by unique lymphocyte receptors (of B or T cells)
NB: T cells only recognize antigens displayed with MHC |
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Bursa of Fabricius
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tissue where B cells mature from progenitor cells in chickens
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complement
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a host defense system consisting of soluble and membrane-bound proteins
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chemokines
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small molecules that were originally IDed b/c of their role in attracting cells to a particular region
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cytokines
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molecules that are secreted primarily (but not exclusively) by cells of the immune system; these play an important role in activation and in down-regulating immune responses
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follicle associated epithelium
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that region of the lumenal epithelium that is not covered by mucus
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germinal center
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part of the follicle where antigen-induced B cell differentiation occurs
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hapten and carrier
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hapten- a small molecule (<6kD) that is not immunogenic
carrier- a protein to which a hapten has bound, permitting an anti-hapten immune response |
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hematopoiesis
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process by which various cell types differentiate from a pluripotent stem cell
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immunogenicity
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refers to a molecules that can serve as a stimulus for adaptive immune response
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innate immunity
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component of the immune system in which cells and effectors do not have memory, nor receptors specific for an epitope; immunity present at birth
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mitogen
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polyclonal activator
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PALS
periarteriolar lymphatic sheath |
region containing white pulp
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white pulp
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region of the spleen within PALS; predominantly T cells and where primary T cell responses occur
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tolerance
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refers to the fact that the immune system is not pathologically activated in the presence of its own antigens; the ability for our immune system to tolerate our own cells and not attack
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