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5 Cards in this Set
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- 3rd side (hint)
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Cyclosporine
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Binds to Cyclophiline= Decreases Calcineurin=Decreased Activation of T-Cells Transcription Factor= Decreased IL2, IL3, Interferon Y
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Doc for organ or Tissue Transplantation
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Tacrolimus
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Binds to FK binding protein= Decreases Calcineurin=Decreased Activation of T-Cells Transcription Factor= Decreased IL2, IL3, Interferon Y
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Alternative to Cyclosporine in Liver and Renal Transplant
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MycoPhenolate
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Inhibitor of de novo synthesis of purines
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Cyclosporine side effect
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Nephrotoxicity and gingival over growth
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Tacrolimus Side effect
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Nephrotoxicity
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