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6 Cards in this Set

  • Front
  • Back
Ways bacteria resist antibiotics
1.degrade/alter antibiotic (beta-lactamase)
2.Efflux Pump- pumps it out of the cell (tetracycline)
3. Uptake Reduction
4. Overproduction of target
5. Alteration of Target (penicillin binding proteins change, 50s
what do you need for horizontal gene transfer to occur?
recombination as a double crossover
Transformation
Donor releases free DNA by lysis. DNA attaches to a recipient cell. Gene recombines with the recipient's chromosome
Conjugation
use of the large pili.
When the plasmid transferred to another cell, it drags along the chromosome with it, integration with double cross over
What are transposons
Jumping genes. Carry insertion sequence and other genes. Allow for antibiotic resistance/ resistance Plasmid
Transduction
Utilization of Viruses
Generalized transduction- transfers any bacterial gene
Specialized transduction- transfers only genes adjacent to the site of integration