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29 Cards in this Set

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  • Back
ABO system
blood group polysaccharide antigens
affinity
the force between molecules that impels them to bind to one another (non-covalent)
allotype
antigenic differences within a given class of Ig between members of the same species
allotypic
pertaining to an allotype
Am
IgA allotypes
anti-idiotypic antibodies
antibodies that are specific for a set of idiotypes
avidity
the sum of the affinities when two molecules are interacting
class of antibody
antibody isotypes
complementary determining region (CDR)
that part of the variable region which is hypervariable between antibodies
constant region
that part of the Ab molecule that is the same for all Ab of one class within an isotype
crossreactive
refers to the fact that some antibodies will bind to antigens that are closely related
Gm
IgG allotypes
half life
the period during which the number of Ab molecules is decreased by 50%
HAMA (human anti-mouse antibodies)
human responses to mouse antibodies injected for therapeutic value
hybridoma
cell that is the result of fusion of a tumor cell with a normal cell
idiotope
one component within the antibody hypervariable region that is unique
idiotype
the sum of the idiotypes
isohemagglutinin
IgM antibodies that are specific for the A, B antigens on the RBCs
J chain
the joining chains of the IgM and IgA antibodies
kappa
one of the two light chain constant regions (the other is lambda)
Km
the kappa chain allotypes
lambda
one of the two light chain Ab constant regions (the other is kappa)
papain
an enzyme that cleaves the IgG antibody molecule above the S-S bond
pepsin
an enzyme that cleaves the IgG antibody molecule below the S-S bond
proteolysis
cleavage of proteins by enzymes
reaginic
related to allergies and IgE Abs
secretory component
the component of the IgA dimer that is retained when dimeric IgA is secreted to lumen
subclass
subclass within the class of Abs (e.g. IgG1, IgG2, IgG3)
variable region
the region of Abs that veries from one Ab to another even within one class