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29 Cards in this Set
- Front
- Back
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ABO system
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blood group polysaccharide antigens
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affinity
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the force between molecules that impels them to bind to one another (non-covalent)
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allotype
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antigenic differences within a given class of Ig between members of the same species
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allotypic
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pertaining to an allotype
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Am
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IgA allotypes
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anti-idiotypic antibodies
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antibodies that are specific for a set of idiotypes
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avidity
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the sum of the affinities when two molecules are interacting
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class of antibody
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antibody isotypes
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complementary determining region (CDR)
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that part of the variable region which is hypervariable between antibodies
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constant region
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that part of the Ab molecule that is the same for all Ab of one class within an isotype
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crossreactive
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refers to the fact that some antibodies will bind to antigens that are closely related
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Gm
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IgG allotypes
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half life
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the period during which the number of Ab molecules is decreased by 50%
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HAMA (human anti-mouse antibodies)
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human responses to mouse antibodies injected for therapeutic value
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hybridoma
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cell that is the result of fusion of a tumor cell with a normal cell
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idiotope
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one component within the antibody hypervariable region that is unique
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idiotype
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the sum of the idiotypes
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isohemagglutinin
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IgM antibodies that are specific for the A, B antigens on the RBCs
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J chain
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the joining chains of the IgM and IgA antibodies
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kappa
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one of the two light chain constant regions (the other is lambda)
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Km
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the kappa chain allotypes
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lambda
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one of the two light chain Ab constant regions (the other is kappa)
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papain
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an enzyme that cleaves the IgG antibody molecule above the S-S bond
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pepsin
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an enzyme that cleaves the IgG antibody molecule below the S-S bond
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proteolysis
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cleavage of proteins by enzymes
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reaginic
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related to allergies and IgE Abs
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secretory component
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the component of the IgA dimer that is retained when dimeric IgA is secreted to lumen
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subclass
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subclass within the class of Abs (e.g. IgG1, IgG2, IgG3)
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variable region
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the region of Abs that veries from one Ab to another even within one class
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