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13 Cards in this Set
- Front
- Back
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IgD (Form, Function?)
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Mainly B Cell antigen receptor, monomer
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IgM (Form, Function?)
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Major BCR, first isotype secreted by B clones, very good complement activation, neutralizing, pentamer
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IgG (Form, Function?)
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Most abundant, opsonization, only one that can cross the placenta via FcRn, ADCC, activates compliment, neutralization, B cell regulation, monomer
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IgA (Form, Function?)
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mucosal immunity, neonatal immunity in breast milk, crosses gut epithelial via FcRn, nuetralization, activates compliment, dimer
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IgE (Form, Function?)
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allergic reactions, clears parasites, works with eosinophils/mast cells, monomer
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AB class switch
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IFNgamma (IgG), IL4+IL5 (IgE), TGFbeta (IgA)
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Acute Phase Response
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TNFalpha, IL1, IL6
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Antiviral
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IFNalpha, IFNbeta, IFNgamma
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Cell Growth
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IL2(T), IL3 + GMCSF, IL7 (BT), IL12(Th1)
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Cell Differentiation
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IL4 (Th2), IL10 (Th2), IL17, IFNgamma
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Chemoattraction
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IL8
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Immunosuppression
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IL10, IL13, TGF-beta
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Inflammation and Fever
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TNF-alpha, IL1
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