Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
41 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Nonspecific defenses against fungal infections
How many? |
4
List |
Physical Chemical Mechanical barriers
Inflammation |
|
|
4 Nonspecific defenses against fungal infections
List |
Physical Chemical Mechanical barriers inflammation |
|
|
|
Specific defenses against fungal infections
How many? |
2
List |
Ab Responses Cell-mediated immunity |
|
|
2 specific defenses against fungal infections
List |
Ab responses Cell-mediated responses |
|
|
|
2 specific defenses against fungal infections
___________ Cell-mediated responses |
Ab responses
Importance |
Minor role |
|
|
2 specific defenses against fungal infections
ab responses ______________ |
Cell-mediated responses
Importance |
Most important |
|
|
2 specific defenses against fungal infections
Ab responses vs. Cell-mediated immunity |
Minor vs. most important |
|
|
|
2 specific defenses against fungal infections
Cell-mediated immunity
Type of hypersensitivity |
Delayed type hypersensitivity
Ab responses or Cell-mediated ? Importance? |
Cell-mediated immunity Most important |
|
|
Parasitic diseases: Protozoa
Nonspecific defenses |
Same as fungal
List |
Chemical Physical Mechanical barriers
Inflammation |
|
|
Parasitic diseases: Protozoa
Specific defenses
How many? |
2
List |
Humoral cell mediated immunity |
|
|
Parasitic diseases: Protozoa
2 specific defenses
List |
Humoral immunity Cell mediated immunity |
|
|
|
Parasitic diseases: protozoa
Humoral immunity
Key player |
Abs
Main target |
Organisms that invade the bloodstream |
|
|
Parasitic diseases: protozoa
Humoral immunity
Key player: Abs Main target |
Organism that invade the bloodstream
Examples |
Malaria Trypanosomiasis |
|
|
Parasitic diseases: protozoa
Humoral immunity
Key player: abs Main target: organisms that invade the bloodstream
How many examples? |
2
List |
Malaria Trypanosomiais |
|
|
Parasitic diseases: protozoa
Humoral immunity
Mechanism |
Opsonization Binding of C' |
|
|
|
Parasitic diseases: protozoa
Humoral immunity
How many mechanism there are? |
2
List |
Opsonization
Binding of C' |
|
|
Parasitic diseases: Protozoa
Humoral immunity _______________ |
Cell-mediated immunity
Type of hypersensitivity |
Delayed type hypersensitivity |
|
|
Parasitic diseases: protozoa
Cell-mediated immunity
Type of hypersensitivity |
Delayed type hypersensitivity |
|
|
|
Parasitic diseases: Protozoa
Cell-mediated immunity
Main target |
Organisms that invade the tissues
Example |
Leishmaniasis |
|
|
Parasitic diseases: Protozoa
Cell-mediated immunity
Main target: Organisms that invade the tissues
Example |
Leishmaniasis
Humoral or Cell-mediated immunity Type of hypersensitivity? |
Cell-mediated
Delayed type |
|
|
Parasitic disease: Protozoa
Humoral vs. cell-mediated immunity
Main target |
Organisms that Invade the bloodstream vs. tissues
Examples |
Malaria, trypanosomiasis vs. Leishmaniasis |
|
|
Helminths
Mechaisms of immunity How many? |
2
List |
IgE mediated Eosinophil mediated |
|
|
Helminths
2 mechanism of immunity |
IgE mediated Eosinophil mediated |
|
|
|
Helminths
2 mechanism of immunity
___________ Eosinophil mediated |
IgE mediated
Type of hypersensitivity |
Type I |
|
|
Helminths
Mechanisms of immunity
IgE mediated
Type of hypersensitivity |
Type I |
|
|
|
Helminths
Mechanism of immunity IgE-mediated
Mechanism |
1. IgE binds to mast cells 2. Histamine release 3. + vaso dilation and peremability 4. Expulsion of worms from gut and attraction of wbc (esp?) |
Eosinophils |
|
|
Helminths
Mechanism of immunity IgE-mediated
How many steps? |
4
List |
1. IgE binds to mast cells 2. Histamine release 3. + vaso dilation and premeability 4. Expulsion of worms from gut and attraction of WBC (esp. eosinophils) |
|
|
Helminths
Mechanism of immunity
IgE-mediated _____________ |
Eosinophil-mediated
Mechanism |
Damage worms by ADCC |
|
|
Helminths
Mechanism of immunity
Eosinophil mediated
Mechanism |
Damage worms by ____ |
ADCC |
|
|
Ways helminths can escape immune responses
How many? |
3
List |
Worms 1. Motility 2. Antigenic mimicry 3. Some can suppress the immune response
|
|
|
3 Ways helminths can escape immune responses
List |
Worms 1. Motility 2. ________+description 3. Some can suppress the immune response |
Antigenic mimicry Worms disguise themselves with an outer coat of host Ags |
|
|
3 ways helminths can escape immune responses
Antigenic mimicry Description |
Worms disguise themselves with an outer coat of host Ags
Example |
Schistosomiasis |
|
|
3 ways helminths can escape immune responses
Antigenic mimicry Example |
Schistosomiasis |
|
|
|
Helminths
What can occur with pathology? |
Chronic infections
Why? |
Hypersensitivity Rxns |
|
|
Ways Protozoa can escape Immune response |
Different developmental stages have different antigens
Antigenic variation
Survival in macrophages
some: Immune response suppression |
|
|
|
Ways protozoa can escape immune response
Different developmental stages have different antigens
___________
Survival in macrophages
Some: suppression of immune response |
antigenic variation
Def? |
Change of parasite Ag during the course of infection |
|
|
Antigenic variation
Def? |
Change of parasite Ag during the course of infection
Examples |
Malaria Trypanosomes |
|
|
Antigenic variation
Examples |
Malaria Trypanosomes |
|
|
|
Ways protozoa escape immune responses
Different developmental stages have different antigens
Antigenic variation
______________
Some: suppression of immune response |
Survival in macrophages
Examples |
Toxoplasma Leishmania |
|
|
Tests for Fungal Antibodies
Results that are indicative of a current infection |
Negative to positive
4 fold rise in Ab titer over time
Single high titer |
|
|
|
Tests for fungal antibodies
How many results that are indicative of a current infection? |
3
List |
Negative to positive
3 fold rise in Ab titer
Single high titer |
