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20 Cards in this Set

  • Front
  • Back
Normal Immune Response
effective protection from infection and disease in response to antigen presented
Immunodeficiency
ineffective protection from infection/disease due to inactive receptors involved in immune recognition
inflammatory reaction

mutations that render the receptors alway active


Hypersensitivity> exaggerated immune response



autoimmune
immune system fails to distinguish self from non-self and mounts a response normal self tissue leading to self destruction
How age affects immunity

thin skin


decrease in GI tract acidity


shallow breathing (decrease in gas exchange)


less acidic urine


less elastic bladder


decrease immune response


platelet aggregation

How does exercise affect immune system

moderate, regular exercise- boosts immune system responses


strenuous/intense exercise- impairs immune system function temporarily but can have cumulative effects



Neck Check

symptoms above the neck: stuffy nose, sneezing, scratchy throat


- if symptoms persist, exercise at half speed


- after 10 mins. symptoms alleviated, exercise can completed as usual


- if symptoms worsen, cease exercise and rest


* if symptoms BELOW neck, muscle pain, cough, diarrhea and vomiting- do not initiate exercise

Best ways to prevent infection

Hand washing


disinfection


standard precautions



latrogenic immunodeficiency
immunodeficiency caused by a physician, such as use of immunosuppressive drugs, radiation therapy, or spenectomy
AIDS

Acquired Immunodeficiency Syndrome


-caused by HIV


-retrovirus that infects T4 helper lymphocytes


-susceptible to opportunistic infections


-decline in death due to improved medical management not behavior changes

HIV

Human Immunodeficiency Virus


-no cure or vaccine


-focus on prevention


-Risk factors: body fluid exchange, intravenous drug use, protected sex, low SES

PTA implications : HIV/AIDS

PTA not at high risk, unless doing wound care


-occupational transmission occurs from needle stick, non-intact skin contaminated ( use band-aids and gloves if PTA has open areas


-important to be discreet and non-judgemental


-be aware of pt. depression/anxiety


-education to pt. for good nutrition


-reduce infection risk



Chronic Fatigue Syndrome (CFS)

not a single disease, multifactorial


-virus, immune dysfunction, neuro, cns dysfunction, muscle structure, sleep patterns, genetics, childhood inactivity etc...


-no diagnostic test


-other dx must be ruled out


-common in females


-29-35 yrs. old


-duration 3-9 yrs


-no cure

PTA Implications for CFS

-pt. with CFS < 2 yrs. more likely to improve


-controlled, progressive exercises found to be beneficial


-similar guidelines as fibromyalgia


-over exertion with daily activities can exacerbate fatigue symptoms


-do not have internal mechanisms to alert to stop activity

Type 1 Hypersensitivity

-hayfever


-rashes


-anaphylactic shock


-wheezing


-increased mucous secretions


-bronchospasm


-hypotension



Type II Hypersensitivity

body's own tissue is recognized as foreign or nonself


-cell membrane destroyed


-blood transfusion reactions


-hemolytic disease of newborn


Myasthenia gravis

Type III hypersensitivity

acute inflammation


local tissue injury


vasculitis to skin


joints> causing synovitis


kidneys> causing nephritis


pleura> causing pleuritic


Systemic lupus erythematosus is classic example

Type IV Hypersensitivity

delayed response, reaction occurs after sensitization


-contact dermatitis from something topical


-latex sensitivity


-TB test

PTA implications for hypersensitivity

-review with pt. for allergens


-ask if they use Epipen


-caution with latex gloves, therabands


-caution with adhensives


-awareness of contact reactions to gels, lotions, creams used with treatment


-first exposure may be ok but second contact may cause reaction