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3 Cards in this Set

  • Front
  • Back
VIRUS - Cell Mediated Adaptive response
TH1 and CD8 control intracelllular infection; lyse infected cells-->resolution

APC phagocytose free virion
NK and APC rel early cytokines
APC present to TH0:
upreg CD80/86, MHC on APC
TH0-->TH1, TH2; upreg MPh, PMN
CTL activated
B cells activated
VIRUS - Humoral Adaptive response
Prevent spread by blocking extracellular virions

Ig neutralize, opsonize virus;
removed via ADCC, NK (with Ig providing specificity
VIRUS - Innate response
Infected cells, produce IFN-α/ß, IL-6, IL-12, chemokines to attract NKs and DCs

complement-mediated lysis of virions
opsonization and phagocytosis of virions