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3 Cards in this Set
- Front
- Back
VIRUS - Cell Mediated Adaptive response
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TH1 and CD8 control intracelllular infection; lyse infected cells-->resolution
APC phagocytose free virion NK and APC rel early cytokines APC present to TH0: upreg CD80/86, MHC on APC TH0-->TH1, TH2; upreg MPh, PMN CTL activated B cells activated |
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VIRUS - Humoral Adaptive response
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Prevent spread by blocking extracellular virions
Ig neutralize, opsonize virus; removed via ADCC, NK (with Ig providing specificity |
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VIRUS - Innate response
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Infected cells, produce IFN-α/ß, IL-6, IL-12, chemokines to attract NKs and DCs
complement-mediated lysis of virions opsonization and phagocytosis of virions |